Arterial and Venous systems and Lymphatics Flashcards

1
Q

Which of the following factors affects pulse pressure?

  • Vascular elastance
  • arterial compliance
  • stroke volume
  • all of the above
  • the first and third only
A

vascular elastance AND stroke volume

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2
Q

Which of the following is the most important means for the exchange of substances between the blood and the interstitial fluid?

  • blood hydrostatic pressure
  • osmosis
  • capillary oncotic pressure
  • diffusion
  • interstitial fluid hydrostatic pressure
A

diffusion

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3
Q

Vascular distensibility equation

A

Vascular distensibility = increase in volume/ (increase in pressure * original volume)

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4
Q

What happens when the distensibility is decreased in veins when it comes to blood storage?

A

the amount of blood stored there decreases

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5
Q

Vascular compliance (capacitance) equation:

A

Vascular compliance (capacitance) = (increase in volume)/(increase in pressure)

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6
Q

What characteristic of blood vessels does capacitance describe?

A

distensibility

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7
Q

What is capacitance inversely proportional to?

A

elastance

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8
Q

How does a greater amount of elastic tissue in blood vessels affect compliance? why?

A

the blood vessels have a lower compliance because due to the higher amount of elastic tissue the blood vessels have a higher elastance

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9
Q

Pulse pressure equation

A

Pulse pressure = stroke volume/arterial compliance

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10
Q

What occurs at the sharp incisura?

A

the closing of the aortic valve

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11
Q

What is the progressive reduction of the pulsations in the periphery known as?

A

damping of the pressure pulses

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12
Q

Why does the mean arterial pressure lie closer to diastolic than to systolic?

A

because about 60% of the cardiac cycle is spent in diastole and 40% in systole

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13
Q

Mean arterial pressure equation

A

Mean arterial pressure = diastolic pressure + 1/3 pulse pressure

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14
Q

What is central venous pressure?

A

pressure in the right atrium

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15
Q

What is the most important factor regulating vasomotion?

A

concentration of oxygen in the tissues

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16
Q

Net filtration Pressure equation

A

Net filtration pressure (NFP) = Capillary pressure (outward)(Pc) - interstitial fluid pressure (inward) (Pif) - plasma colloid osmotic (oncotic) pressure (inward) ( np) + interstitial colloid osmotic (oncotic) pressure (outward)(nif)

NFP = Pc - Pif - np + nif

17
Q

The least amount of damping of the pressure pulses would occur in which of the following components of the circulatory system?

  • arterioles
  • venules
  • femoral artery
  • capillaries
A

femoral artery

18
Q

What are the comparison of distensibility between arteries and veins?

A
  • veins are about 8 times more distensible than arteries
  • Pulmonary vein distensibilities are about the same as for systemic veins
  • pulmonary artery distensibilities are about 6 times that of systemic arteries
19
Q

What is capacitance directly proportional to and inversely proportional to?

A

it is directly proportional to volume and inversely proportional to pressure

20
Q

Where is capacitance higher? veins or arteries

21
Q

How does age affect capacitance and what does this cause?

A

it decrease with age and can be a cause of hypertension

22
Q

What are the factors that increase venous return and increase right atrial pressure?

A
  • increased blood volume
  • increased peripheral venous pressures due to increased large vessel tone
  • dilation of arterioles
23
Q

What is the precapillary sphincter’s function?

A

it is smooth muscle fiber that encircles capillary at point where it orginates from a metarteriole and controls how much blood will enter the system

24
Q

What are starling forces and what do they determine?

A

they are the forces inside and outside the capillary that determine direction of diffusion into or out of a capillary

25
What are the 4 starling forces for a capillary and which direction are the going?
1. Capillary pressure (outward) 2. interstitial fluid pressure (inward) 3. Capillary plasma colloid osmotic pressure (inward) 4. interstitial fluid colloid osmotic pressure (outward)
26
What are the sum of the starling forces equal too?
net filtration pressure
27
Net filtration pressure equation
NFP = Capillary pressure - intersitial fluid pressure - plasma colloid osmotic pressure + interstitial colloid osmotic pressure
28
What is the capillary filtration coefficient?
takes into consideration the number and size of pores to account for the differences in leakiness for different capillaries
29
What are the 3 forces moving fluid outward?
capillary pressure NEGATIVE intersitial free fluid pressure intersitial fluid colloid osmotic pressure
30
What is the force moving fluid in to the capillary?
plasma colloid osmotic pressure
31
What is the net outward force for a arterial end capillary?
13 mm hg
32
What is the net inward force at venous end of capillary?
7 mm Hg which is the net reabsorption force
33
What are the 4 factors that increase lymph flow and also interstitial fluid pressure?
- Elevated capillary hydrostatic pressure - decreased plasma colloid osmotic pressure - increased interstitial fluid colloid osmotic pressure - increased permeability of capillaries
34
Rate of lymph flow equation
Rate of lymph flow= interstitial fluid pressure X activity of lymphatic pump