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Blood Micro > Arbovirus > Flashcards

Arbovirus Flashcards

1
Q

Members of arbovirus family

A

Togavirus
Flavivirus
Bunyavirus
Reovirus

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2
Q

Flavivirus includes which important arboviral diseases of man

A

Yellow fever
Japanese encephalitis
Dengue fever

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3
Q

Dengue virus transmission

A

Bite of an female aedes mosquito
(Aedes aegypti & Aedes albopictus)

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4
Q

Dengue fever also called

A

Break bone fever because it causes severe joint and muscle pain

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5
Q

Dengue virus types

A

DEN-1
DEN-2
DEN-3
DEN-4

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6
Q

Dengue clinical variants

A

Classical dengue fever
Dengue hemorrhagic fever
Dengue shock syndrome

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7
Q

Principal symptoms of dengue

A

High fever and at least two of the following
-severe headache
-severe eye pain
-joint/muscle/bone pain
-rash
-low wbc

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8
Q

Classical dengue fever clinical presentation

A

Fever biphasic
-initial phase few hours to 2 days
-3 to 7 days remission
-second phase 1 to 2 days
Rash
-maculopapular

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9
Q

Dengue hemorrhagic fever clinical presentation

A

All symptoms of classical dengue plus
-bleeding from nose, gums or under the skin causing purplish bruises
-GIT bleeding
-can cause death

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10
Q

Dengue shock syndrome clinical presentation

A

All symptoms of CDF & DHF plus
-massive bleeding
-shock
-vomiting
-hypothermia
-usually in children experiencing their second dengue infection

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11
Q

Lab diagnosis for dengue

A

CBC
Hematocrit
Platelet count
Immunological tests
Chest xray

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12
Q

Lab results for dengue

A

Leukopenia
Thrombocytopenia
ALT/AST elevated
Elisa (IgM and IgG)
PCR and culture
Pleural effusion in hemorrhagic fever

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13
Q

WHO criteria for diagnosis of dengue

A

High continuous fever for 2-7 days
Hemorrhagic diathesis
Hepatomegaly
Thrombocytopenia
Hemoconcentration (inc. hematocrit)

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14
Q

Chikungunya fever caused by

A

Arbovirus transmitted by Aedes mosquito

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15
Q

Family of chikungunya virus

A

Togavirus

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16
Q

Aedes mosquito transmit infection through?

A

Mosquito bites and sucks blood containing the virus from an infected person
And passes the virus to healthy people when it bites them

17
Q

Chikungunya clinical features

A

Two phases
-Acute (onset of fever and polyarthralgia)
-Chronic (inflammatory relapses, long-standing rheumatism)

18
Q

Arthralgia features in Chikungunya

A

Multiple joints
Bilateral and symmetrical
Hands and feet commonly effected
Pain worse in the morning
Swollen and painful joints
Arthritis may last for weeks or months

19
Q

Diagnosis for Chikungunya

A

Elisa (IgM)
Pcr

20
Q

Preventive measures

A

Using insect repellents
Using mosquito nets or screens
Eliminating stagnant water
Aerosol spray of malathion to stop transmission

Blood Micro (5 decks)

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