Approach to Movement Disorders Flashcards

1
Q

What are the two main classifications of movement disorders

A

Bradykinetic

Hyperkinetic

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2
Q

What causes Idiopathic Parkinson’s Disease

A

caused by a depletion of dopamine in the nigrostriatal system, disrupting DA and Acth balance

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3
Q

What is Myerson’s sign

A

repetitive tapping leads to sustained blinking

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4
Q

Describe the features of Progressive Supranuclear Palsy

A

Bradykinesia and rigidity

Loss of voluntary control of eye movement (vertical gaze)

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5
Q

What is the “kicker” feature that separated Multiple System Atrophy

A

Pronounced Autonomic dysfunction.

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6
Q

Describe Cortical Basal Degeneration

A

both cortical and basal ganglionic dysfunction

cortical sensory loss, apraxia, myoclonus or aphasia

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7
Q

How effective are antiparkinsonian drugs against the akinetic rigid syndromes

A

not effective but its all we have!!!

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8
Q

What is athetosis

A

writhing, sinuous movements

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9
Q

What is dystonia

A

sustained muscle contractions that produce twisting and repetitive movements and abnormal postures

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10
Q

What is Ballism

A

large amplitude, flinging movement

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11
Q

What is a tic

A

brief rapid repetitive seemingly purposeless stereotyped action that may involve single or multiple muscle groups

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12
Q

How long to HD patients live after their dx

A

15 years

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13
Q

what medication is used to treat movement in HD

A

tetrabenazine

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14
Q

what is the etiology of sydenham’s chorea

A

mainly in children and adolescents as a complication of previous infection with GROUP A STREP

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15
Q

What is the inheritance of idiopathic Torsion Dystonia

A

AD or AR or X

when you get it you got it for life

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16
Q

what are some clinical findings with Idiopathic torsion dystonia

A

Torticollis
Blepharospasm
oromandibular dystonia

17
Q

how does focal torsion dystonia differ from the idiopathic version

A

dystonia in a specific area

18
Q

What are the clinical features of Wilsons Disease

A

Brady and Hyperkinetic features

  • resting or postural tremor
  • Choreiform movements
  • Rigidity
  • Bradykinesia
  • Psychosis/Hallucinations
19
Q

What is the treatment of wilsons disease

A

penicillamine

20
Q

What defines Gilles De La Tourettes syndrome

A

Chronic, Multiple motor and vocal tics with onset before 21

21
Q

Define briefly each of these words

Coprolalia
Echolalia
Echopraxia
Palilalia

A

Vulgar speech
Copy Words
Copy movements
Repetition of words or phrases

22
Q

What is the treatment of tourettes

A

Clonidine
Haloperidol
Phenothiazines

23
Q

What is the treatment for essential tremor

A
B-blocker
Primidone
Benzo
Topiramate 
brain stimulation