APPROACH TO CARDIOMYOPATHIES

Question 1

Definition and DDx (6): Primary Cardiomyopathy

Answer 1

Diseases that solely or predominantly involve the myocardium. Can be genetic, acquired or mixed.

Hypertrophic Cardiomyopathy
Long QT Syndrome
Brugada Syndrome
Dilated Cardiomyopathy
Myocarditis
Takotsubo Cardiomyopathy
Peripartum Cardiomyopathy

Question 2

Definition and DDx (6): Secondary Cardiomyopathy

Answer 2

Heart muscle disease associated with specific systemic diseases.

TOXIN

INFILTRATIVE
Amyloidosis

STORAGE
Hemochromatosis

AUTOIMMUNE
Scleroderma
Systemic Lupus Erythematosus
Rheumatoid Arthritis
Dermatomyositis

METABOLIC
Nutritional: thiamine deficiency
Endocrine: diabetes, hyperthyroid / hypothyroid
Electrolyte: hypophosphatemia, hypocalcemia
Neuromuscular Disease