Applied Digestive System Flashcards

1
Q

Stages of digestion

A

1) ingestion
2) propulsion
3) mechanical/physical digestion
4) chemical digestion
5) absorption
6) defecation

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2
Q

Faecal formation

A

Stomach&raquo_space;> small intestine&raquo_space;> large intestine
Key players in the large intestine:
- fermentation
- gut bacteria
- water and cellulose
Faeces is moved from the large intestine into the rectum - muscular chamber filled with nerves.
It is felt as an urge to defecate. The rectum is able to detect the type of material in the rectum.
Parasympathetic activity leads to mass action contraction. The increase in abdominal pressure assists the process if the time is right.
Malodorous wind or bowel movements are an indication of stomach upset.

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3
Q

The viscous circle of constipation

A
  • your patient will present with low appetite
  • overloaded rectum affects colon mobility
  • transverse colon lies beneath the stomach which once overloaded it compresses the stomach
  • displaced stomach affects appetite
  • reluctance to eat slows general mobility
  • eating triggers peristalsis
  • increases constipation
  • patients with mobility issues more likely to have reluctance to drink to avoid needing to pass urine
  • increases constipation
  • results in more urgent need to pass urine or open bowels&raquo_space;> potential UTI
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4
Q

Stool assessment

A

Frequency
Odour
Volume
Colour
Presence of blood or mucous
Pain
Effort
Abdominal tenderness or distension
Weight loss or loss of appetite
Nausea and vomiting
Associated urinary symptoms
Stool culture
Capacity
Previous illness
Allergies or food intolerances
Any sudden changed
»> child specific:
Any early difficulties
Time frame of constipation
Was meconium passed appropriately
Anal canal present at birth
Describe potty training experience
Current toilet habits
Childs behaviour when passing stool
Awareness and response to urge

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5
Q

Common causes of constipation

A
  • obstruction
  • conditions e.g. Ehlers Danlos syndrome
  • poor diet&raquo_space;> lack of fibre
  • medications&raquo_space;> antidepressants or hypotension medications can cause constipation as a side effect
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6
Q

Other reasons for being more susceptible to constipation

A
  • being an older adult
  • being female
  • being dehydrated
  • eating a low fibre diet
  • little or no physical activity
  • taking certain medications e.g. sedatives, opioids pain meds, antidepressants, hypotension meds
  • mental health conditions e.g. depression, eating disorders
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7
Q

Patient presentation of constipation

A
  • abdominal bloating
  • BO less than 3 times a week or more than 3 per day of type 1 or 2
  • pain upon defecation
  • rectal bleeding
  • spurious diarrhoea - overflow
  • lower back pain
  • headaches
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8
Q

What can we do to prevent (recurrence)?

A
  • important to treat constipation before considering prevention or recurrence
  • high enough doses of medications for long enough
  • consider damage to the rectum and the time required for full recovery&raquo_space;> in childhood it will take as long as the condition has existed to recover
  • encourage a high fibre diet
  • reduce processed foods
  • encourage fluids
  • encourage regular exercise
  • manage stress
  • do not ignore the urge to pass stool
  • encourage a regular schedule for bowel movements
  • manage medications
  • stool assessment
  • administer laxatives e.g. stool softeners, osmotic and stimulant laxatives
  • assess mental health stressors
  • in children consider structural congenital and genetic causes as well as obese
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9
Q

Diarrhoea

A

> > > At least 3 loose, liquid or watery bowel movements each day
Secretory diarrhoea
- sodium is prevented from being absorbed into the blood stream
- draws water into the bowel
- may be caused by bacterial infection
Osmotic diarrhoea
- unabsorbed nutrients draw water into the bowel

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10
Q

Causes of diarrhoea

A
  • viruses
  • bacteria and parasites
  • medications
  • lactose intolerance
  • digestive disorders
  • artificial sweeteners/foods
  • surgery
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11
Q

Patient presentation with diarrhoea

A
  • abdominal pain or cramping
  • bloating
  • nausea and vomiting
  • fever
  • blood or mucous in the stool
  • urgent need to have a bowel movement
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12
Q

Irritable bowel syndrome

A
  • it is important to differentiate IBS, in which no pathological process of the GI tract has been identified, from IB, in which a well defined pathological process is identifiable
  • IBS is a complex entity that remains incompletely understood
  • presents with alternating diarrhoea and constipation accompanied by abdominal cramping pain in the absence of any identifiable pathological process in the GI tract
  • the quantity of symptoms is not as important as their effect of the normal lifestyle of an individual
  • those with IBS may miss work, curtail their social life and avoid sexual intercourse
  • primarily a disorder of bowel motility
  • the Moyo wave activity of the colon, which usually occurs at a rate of six times per minute, it markedly increased in IBS
  • the sensory response to distension and stimulation seems to be heightened
  • could be genetic pastors of environmental
  • episodic infection, psychological stressors or dietary patterns
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13
Q

Obstruction

A
  • most common obstruction in adults is cancer
  • in children tumours are much less common
  • more common obstructions in infants is intussusception
  • most tumours of the large bowel are adenocarcinomas
  • these tend to grow slowly and remain asymptomatic for long periods
  • tumours in the rectum and sigmoid and descending colon grow circumferentially and constrict the intestinal lumen
  • tumours in the ascending colon are usually large and palpable
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14
Q

GI disease

A

> > > Reduced saliva = xerostomia
Symptoms
- dry mouth
- dental caries
- difficulty swallowing
Causes
- caused by drugs&raquo_space;> radiation therapy

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15
Q

Dysphasia

A

Difficulty swallowing&raquo_space;> CNS disease - stroke
Physical blockage&raquo_space;> oesophageal cancer

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16
Q

Inflammatory bowel disease&raquo_space;> Corona disease

A
  • Deep inflammation that can affect all the gut tube&raquo_space;> mouth to anus
  • Abdominal pain
  • Diarrhoea
  • Fistulae
17
Q

Inflammatory bowel disease&raquo_space;> Ulcerative colitis

A
  • only affects the colon&raquo_space;> starting at the rectum an working backwards
  • superficial ulceration
  • diarrhoea often with blood and mucus
18
Q

Inflammatory bowel disease&raquo_space;> Chrons disease

A
  • cause remains unknown, although a genetic link has been established with ost sufferers having at least one other family member affected
  • CD appears to result from chronic type 1 T helper cell activation
  • leading to immune overstimulation
  • thought to be an autoimmune process
  • resulting in inflammation and tissue injury
  • many of the factors identified in the pathogenesis are influenced by genetic factors
  • the focal inflammation lesions in the crypts of the intestinal mucosa expand ad develop into noncasating (without necrotic centre) granulomas
  • subsequent engorgement and inflammation of surrounding tissue lead to the development of deep linear ulcers in the bowel wall
  • eventually all layers of the GI tract wall may become involved and portion of intestine is affected may become thickened by fibrous scar tissue
  • deep fissures may develop into fistulas which may extend into adjacent tissue of other organs such as the bladder all of even the skin
19
Q

Inflammatory response

A

Inflammation occurs when cells are injured, regardless of the cause of injury
- a protective mechanism that also begins the healing process
Three supposes
1) to neutralise and destroy invading and harmful agents
2) to limit the spread f harmful agents to other tissues
3) to prepare any damaged tissue for repair
Inflammatory reactions increase capillary permeability such that phagocytic cells, complement and antibodies can leave the bloodstream and enter tissues where they are needed
Five cardinal signs
1) redness
2) swelling
3) heat
4) pain
5) loss of function
Any injury to tissue will evoke an inflammatory response
- sources outside the body (exogenous)
- inside the body (endogenous)