Apoptosis Flashcards
1
Q
What causes tumor growth?
A
Too much growth, not enough death
2
Q
Causes of cell death
A
DNA damage, telomere, mitotic failure, immune response, metabolic stress
3
Q
If _______ is not ________, cell must _______
A
error, fixed, die
4
Q
Extrinsic cell death is carried out by ____________
A
Killer T cells
5
Q
Intrinsic cell death is carried out by the release of ______________, which is known as an ___________
A
Cytochrome C, apoptotic stimulus
6
Q
APAF-1
A
“wheel of death”, attracts procaspase-9, which is activated, cleaves and activated executioner procaspases, caspase cascade lyses everything in cell
