Apoptosis

Question 1

Irreversible cell injury Occur in

Answer 1

sever & progressive forms of injury

Question 2

Apoptosis process

Answer 2

Apoptotic cells shrinkage then break up into plasma membrane–bound fragments, called apoptotic bodies → phagocytosis

Question 3

normal phenomenon that serves to eliminate cells that are no longer needed

Answer 3

Physiological Apoptosis

Question 4

Physiological Apoptosis examples

Answer 4

1. During embryogenesis
2. Death of cells that have served their useful purpose
3. Elimination of harmful self- destructive cells

Question 5

Death of cells that have served their useful purpose such as

Answer 5

neutrophils in an acute inflammatory response

Question 6

Example for Elimination of harmful self- destructive cells

Answer 6

self reactive lymphocytes

Question 7

Examples of Pathological apoptosis?

Answer 7

A. DNA damage
B. Odd Cells

Question 8

Radiation and cytotoxic anticancer drugs causese

Answer 8

DNA damage

Question 9

Odd Cells just like

Answer 9

in certain viral infections (HIV infections), transplanted cells.

Question 10

Pathological picture of apaptosis

Answer 10

1. Shrinkage of cells
2. Nuclear fragmentation
3. Formation of apoptotic bodies.
4. Phagocytosis of apoptotic cells, usually by macrophages