Apolipoproteins

Question 1

What induces HMG-CoA reductase

Answer 1

Insulin

Question 2

HMG-CoA step

Answer 2

Converts HMG-COA to mevalonate

Question 3

ApoE

Answer 3

Mediates remnant uptake [Exit out of blood]

Question 4

ApoA-I

Answer 4

Activates LCAT [A-I Activates LCAT]

Question 5

ApoC-II

Answer 5

Lipoprotein lipase cofactor [Cofactor for LPL]

Question 6

ApoB-48

Answer 6

Mediates chylomicron secretion [48 inches of gut]

Question 7

ApoB-100

Answer 7

Binds LDL receptor [100 is the top, it’s the end, it’s where LDL ends it’s trip]

Question 8

Chylomicron Apo proteins

Answer 8

They have everything except B-100 (for LDL)

Question 9

ApoE found on

Answer 9

Everything except LDL (LDL has it’s own B-100)

Question 10

ApoA-I found on

Answer 10

Only Chylomicrons and HDL [Chylomicrons move chol. from Gut to Liver, HDL from Periphery to Liver, both need LCAT to mature]

Question 11

ApoC-II found on

Answer 11

Chylomicron, VLDL, and HDL [Chylomicron and VLDL have lots of fat so need LDL, HDL is just a repository for most things]

Question 12

ApoB-48 found on

Answer 12

Chylomicron and chylomicron remants [From 48 inches of Gut]

Question 13

ApoB-100 found on

Answer 13

VLDL, IDL, LDL [All of the DLs]