APA Diabetes Flashcards

1
Q

How does DM 1 frequently first present?

A

As DKA

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2
Q

When monitoring A1C post changes or with an unstable patient, how often do you re-check A1C?

A

Q3mos

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3
Q

What is the ideal postprandial blood sugar?

A

<180

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4
Q

How often do you monitor A1C in the stable patient?

A

Every 6 months

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5
Q

What is the normal range for FBS?

A

70-100

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6
Q

What FBS range would be considered prediabetic?

A

101-125

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7
Q

What is the diagnostic criteria for DM?

A

FBS> 126 on 2 occasions
>200 random
HgA1C >6.5
2hr GTT >200

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8
Q

Which oral agents are considered sensitizers?

A

Biguanides (Metformin) and TZDs (actos/avandia)

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9
Q

How do sensitizers work?

A

Decrease hepatic production and increase peripheral use: Increases insulin sensitivity by decreasing glycogenolysis & glyconeogenesis in liver and decreasing intestinal absorbtion. Increasing glucose uptake in skeletal muscle.

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10
Q

Sensizters affect postprandial and fasting sugars? True or False

A

True

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11
Q

What are two benefits of sensitzers (Metformin & TZD)

A

Low cost, highly effective and minimal hypoglycemia

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12
Q

What is the main side affect of metformin and how can it be reduced?

A

GI affects, start at low dose and gradually titrate upwards

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13
Q

Which group of sensitizers are contraindicated in heart disease?

A

TZDs

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14
Q

Long term use of metformin can lead to what deficiency?

A

B12

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15
Q

Increased fracture risk, fluid retention, weight gain and GI upset are common side affects of which type of drugs?

A

TZDs Actos/Avandia

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16
Q

Which ODA class is most likely to produce hypoglycemia?

A

Sulfonylureas

17
Q

Do not combine insulin with what other ODA?

A

Meglintides, severe hypoglycemia