Aortic Stenosis Flashcards
Aortic Stenosis Etiology
- calcific/degenerative(50% start as bicuspid)
- rhematic (ass. w/ MS)
- congenital (bicuspid(1-2% of the populateion), membrane)
- supra and subvalvular obstructions
- prosthetic valve dysfunction
aortic stenosis
pathophysiology
- systolic pressure overload
- increase in LVEDP
- ventricular dysfunction may develop late in disease course
- increased risk for endocarditis
- aortic sclerosis
aortic stenosis- pathophysiology
systolic pressure overload leads to
LVH (increased in afterload)
aortic stenosis- pathophysiology
increase in LVEDP leading to
increased LA pressure
aortic stenosis-pathophysiology
increased risk for
endocarditis
aortic stenosis-pathophysiology
aortic sclerosis occers when
there is valvular thickening but no hemodynamic gradient
a secondary findings in aortic stenosis is
left ventricular hypertrophy
in aortic stenosis is pulse pressure wide or narrow
narrow (pulse pressure is the difference between systolic and diastolic pressure-it is wide in AI and narrow in AS)
aortic stenosis- physical signs
symptoms
- angina
- dyspenia
- syncope
- sudden death
aortic stenosis- physical signs
murmur
harsh systolic ejection murmur right upper sternal border (RUSB) crescendo-decrescendo
aortic stenosis- physical signs
decreased or absent
A2 (valve doesn’t move)
aortic stenosis-physical signs
decreased and delayed
carotid upstroke with bruit/thrill transmitted from AoV.
aortic stenosis
echo (valvular)
- thickened aortic leaflets
- decreased vvalve opening
- post-stenotic dilation of the aorta- thought to be caused by abnormal turbulence and wall stree (remember there is low pressure in the aorta (systolic BP) but high pressure in the LV)
- left ventricular hypertrophy
aortic stenosis- echo (valvular)
post stenotic dilation of the aorta thought to be caused by
abnormal turbulence and wall stress. (remember there is low pressure in the aorta (systolic BP) but high pressure in the LV)
aortic jet velocity(m/s)
mild
moderate
severe
mild- 2.6-2.9
moderate 3.0-4.0
severe >4
aortic stenosis mean gradient (mmHg)
mild
moderate
sevvere
mild- <20
moderate 20-40
severe >40
Aortic stenosis AVA(cm2)
mild
moderate
severe
mild- >1.5
moderate- 1.0-1.5
severe <1.0
aortic stenosis indexed AVA (cm2/m2)
mild
moderate
severe
mild- >.85
moderate- 0.60-0.85
severe- <0.6