Anxiolytics

Question 1

Benzodiazepines

Answer 1

*pams and lams*
diazepam (Valium)
clonazepam (Klonopin)
alprazolam (Xanax)
lorazepam (Ativan)
chlordiazepoxide

Question 2

Benzodiazepine use

Answer 2

anxiety

light anesthesia

Question 3

Benzodiazepine Antidote

Answer 3

Flumazenil

Question 4

Benzodiazepine MOA

Answer 4

bind to specific GABA receptor sites resulting in a calming effect

Question 5

Benzodiazepine AE

Answer 5

ataxia
drowsiness
orthostatic hypotension

Question 6

Benzodiazepine Contra

Answer 6

pregnancy/BF
narrow angle glaucoma
shock
coma
caution in elderly & history drug abuse/addiction

Question 7

Benzodiazepine NI

Answer 7

do not combine with other anti-anxiety meds
no alcohol
no caffeinated or nicotine products
risk for tolerance and addiction
fall precautions

Question 8

Z-hypnotics use

Answer 8

promote REM sleep

Question 9

Z-hypnotics

Answer 9

Zolpidem (Ambien)
Zaleplon (Sonata)
EsZopiclone (Lunesta)

Question 10

Z-hypnotics MOA

Answer 10

bind selectively to GABA receptor sites

Question 11

Z-hypnotics AE

Answer 11

amnesia
ataxia
sleep psychosis
nightmares
rapid onset of effect

Question 12

Z-hypnotics NI

Answer 12

take just before going to bed

fall precautions

Question 13

Melatonin Agonists

Answer 13

Ramelteon (Rozerem)

Question 14

Ramelteon MOA

Answer 14

Melatonin receptor agonist

Question 15

Ramelteon AE

Answer 15

sexual side effects
headache
dizziness

Question 16

Nonbenzodiazepine

Answer 16

Buspirone (BuSpar)

Hydroxyzine (Vistaril)

Question 17

Buspirone takes effect in how long

Answer 17

4-6 weeks

Question 18

Buspirone & Hydroxyzine AE

Answer 18

headache
dizziness
light-headedness
dream disturbances
nausea
insomnia

Question 19

Buspirone & Hydroxyzine NI

Answer 19

stand up slowly
fall precautions
Buspirone has decreased chance for dependence