Antidepressants Flashcards
1
Q
Tricyclic Antidepressants (TCAs)
A
Amitriptyline (Elavil) Nortriptyline (Pamelor) Imipramine HCL (Tofranil) Doxepin (Sinequan) Trimipramine (Surmontil) Clomipramine HCL (Anafranil)
The “in” and “ines”
all have “P”
2
Q
TCA MOA
A
blocks reuptake of norepinephrine
3
Q
TCA contra
A
glaucoma
MI
caution in patients with BPH
4
Q
TCA AE
A
Anticholinergic effects Akathisia Apathy Anhedonia Sedation Orthostatic Hypotension Cardiac arrhythmias
5
Q
Selective Serotonin Reuptake Inhibitors (SSRIs)
A
Fluoxetine (Prozac) Sertraline (Zoloft) Paroxetine (Paxil) Citalopram HBr (Celexa) Escitalopram (Lexapro) Fluvoxamine (Luvox)
6
Q
SSRI MOA
A
blocks the re-uptake and destruction of serotonin
7
Q
SSRI AE
A
Serotonin Syndrome insomnia agitation N/V weight changes sexual dysfunction bruxism apathy low libido sedation
8
Q
SSRI lethality
A
low!
difficult to overdose
9
Q
Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs)
A
Venlafaxine (Effexor) Duloxetine (Cymbalta) Desvenlafaxine (Pristiq) Bupropion (Welbutrin) Levomilnacipran (Fetzima)
10
Q
SNRI MOA
A
increases serotonin, dopamine, and norepinephrine
11
Q
SNRI use
A
PTSD OCD GAD Social anxiety Panic disorder
12
Q
Low dose of SNRI
A
blocks reuptake of serotonin
13
Q
high dose of SNRI
A
blocks reuptake of norepinephrine
14
Q
SNRI AE
A
insomnia agitation headache weight loss sexual dysfunction Serotonin Syndrome
15
Q
Bupropion contra
A
seizure disorder
bulimia or anorexia
abrupt discontinuance of ETOH