Anxiolitice Flashcards

1
Q

Buspirona

A

agonist partial fata de receptorii HT1a

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2
Q

Buspirona administrare

A

5 mg oral de 3 ori pe zi; crestere progresiva pana la 60 mg

efecte adverse: greata, cefalee, ameteli

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3
Q

Alte Tranchilizante

A

hidroxizina, meprobamat

-> anxiolitice, sedative, miorelaxante

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4
Q

Benzodiazepine

A

efect foarte rapid

dezvolta usor taleranta

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5
Q

Benzodiazepine mecanism

A

Stimuleaza situsul benzodiazepinic (ortosteric) situat la nivelul receptorilor GABAergici de tip A.

Favorizeaza actiunea GABA asupra recpetorilor Gaba–> efect inhibitor

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6
Q

Efecte anxiogene

A

beta-carboline

Agonisti de tip invers

Substante ce se fixeaza la situsul benzodiazepinic si ingreuneaza actiunea GABA

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7
Q

Agonist non-diazepinic al receptorilor diazepinici

A

Zolpidem

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8
Q

Zolpidem efect

A

sedativ hipnotic

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9
Q

Zolpidem

A

(derivat imidazopiridinic) este folosit ca hipnotic administrat intern (5 - 10 mg, înainte de culcare).

  • efect numai pe BZ tip 1
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