Anticonvulsivante

Question 1

<p>Anticonvulsivante ce se leaga de PP</p>

Answer 1

<p>Fenitoina, acid valproicm benzodiazepine</p>

Question 2

<p>Timp de injumatatire anticonvulsivante:</p>

Answer 2

<p>12h</p>

Question 3

<p>Eficacitate anticonvulsivante:</p>

Answer 3

<p>80%</p>

Question 4

<p>Medicamentele care blocheaza canale de sodiu sunt eficace in:</p>

Answer 4

<p>Convulsii tonico-clonice, marele rau epileptic

Pot fi daunatoare in micul rau epileptic</p>

Question 5

<p>Med. care blocheaza canale de calciu sunt eficace in:</p>

Answer 5

<p>micul rau epileptic</p>

Question 6

<p>Toate medicamentele anticonvulsivante au si efect:</p>

Answer 6

<p>sedativ</p>

Question 7

<p>Blocante de sodiu anticonvulsivante</p>

Answer 7

<p>Carbamazepina
= eficace si în tratamentul unor dureri nevralgice, în special în nevralgia de trigemen şi glosofaringian şi în durerile tabetice şi este şi un stabilizator al dispoziţiei

Fenitoina</p>

Question 8

<p>Prezinta risc dismorfogen:</p>

Answer 8

<p>Atat epilepsia, cat si antiepileptice</p>

Question 9

<p>Dintre medicamentele antiepileptice, au demonstrat efecte antimaniacale</p>

Answer 9

<p>Carbamazepina, acid valproic</p>

Question 10

<p>Blocante canale de calciu de tip T:</p>

Answer 10

<p>Etosuximida</p>

Question 11

<p>Anticonvulsivante ce potenteaza sistemul GABA:</p>

Answer 11

<p>barbiturice, benzodiazepine</p>

Question 12

<p>Antiepileptice ce scad activitatea unor aminoacizi excitatori in creier:</p>

Answer 12

<p>Lamotrigina</p>

Question 13

<p>Indicatia terapeutica in status convulsivant:</p>

Answer 13

<p>ac. injectabile

diazepam, mai rar fenobarbital sau fosfofenitoina (forma injectabila a fenitoinei)</p>

Question 14

<p>Convulsiile din afara epilepsiei:</p>

Answer 14

<p>Fenobarbital

Diazepam intrarectal</p>

Question 15

<p>Carbamazepina dozare:</p>

Answer 15

<p>100 mg de doua ori pe zi pana la 600 mg pe zi in 2-4 prize</p>

Question 16

<p>Fenitoina are efecte:</p>

Answer 16

<p>Anticonvulsivante, antinevralgice,</p>

Question 17

<p>Fenitoina reactii adverse</p>

Answer 17

<p>hipertrofie gingivala, eruptii, acnee, hirsutism, rar- lupus, Hodgkin0</p>

Question 18

<p>Analog de fenobarbital:</p>

Answer 18

<p>Primidona</p>

Question 19

<p>Benzodiazepine efect anticonvulsivant:</p>

Answer 19

<p>Efect autolimitat

Diazepam
Clonazepam - mic rau
Clobazam</p>

Question 20

<p>Tiagabina</p>

Answer 20

<p>Inhiba recaptarea GABA</p>

Question 21

<p>Vigabatrina</p>

Answer 21

<p>Inhiba Gaba-aminotransferaza</p>

Question 22

<p>Acetazolamina are efect _ prin _</p>

Answer 22

<p>Anticonvulsivant

Inhibarea anhidrazei carbonice</p>

Question 23

<p>Gabapentina, pregabalina</p>

Answer 23

<p>derivati Gaba - antiepileptice in t-c + marele rau si au efecte analgezice</p>

Question 24

<p>(alte medicamente epileptice)</p>

Answer 24

<p>FELBAMAT

RETIGABINA

TOPIRAMAT

LEVETIRACETAM</p>

Question 25

Principalele moduri in care actioneaza medicamentele anticonvulsivante (+exemple):

Answer 25

1. Blocante ale canalelor de Na ( FENITOINA, CARBAMAZEPINA)
2. Blocante ale canalelor de Ca (ETOSUXIMIDA)
3. potentare sistem GABA-ergic (BARBITURICE, BENZODIAZEPINE)