Anxiety et al Flashcards
What is the best psychotherapy for OCD?
Behavioral therapy involving exposure and response prevention
What is the best pharmacotherapy for OCD?
SSRI (fluoxetine, sertraline, and fluvoxamine) => adolescents
- Clomipramine => adolescents
What is the lifetime prevalence of OCD?
2-3%; accounts for 10% of outpatient psychiatric clinic visits
What is the mean age of presentation of OCD?
20yo with male adolescents being more affected than female (but same in adult population)
What is PANDAS?
Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections => group of disorders including OCD, that have been demonstrated to occur after streptococcal infection
Which disorders are associated with OCD?
- MDD
- Social phobia
- Generalized anxiety disorder
- Alcohol use disorders
- Specific phobias
- Panic disorders
- Eating disorders
- Tics and Tourette’s
What neurotransmitter imbalances are seen in anxiety?
- Increased norepinephrine
- Decreased GABA and serotonin
What are medical causes of anxiety disorders?
- Hyperthyroidism
- Vitamin B12 deficiency
- Hypoxia
- Neurological disorders (epilepsy, brain tumors, multiple sclerosis cerebrovascular disease)
- Cardiovascular disease
- Anemia
- Pheochromocytoma
- Hypoglycemia
What are medication/substance induced anxiety disorders?
- Caffeine intake/withdrawal
- Amphetamines
- Alcohol and sedative withdrawal
- Mercury or arsenic toxicity
- Organophosphate or benzene toxicity
- Penicillin/ Sulfonamides
- Sympathomimetics
- Antidepressants
What is the minimum criteria for a panic disorder?
At least one attack with at least one month of the following:
- persistent concern about having additional attacks
- worry about the implication of the attack (losing control or “going crazy”)
- a significant change in behavior related to the attacks
What neurotransmitter differences are seen in anxiety disorders?
- increase norepinephrine
- decrease serotonin and GABA
What is the best treatment for anxiety disorders?
SSRI (especially paroxetine and sertraline)
- use higher doses than for depression
Benzodiazepines are only for immediate relief
What proportion of patients with a phobic disorder also has major depression?
one third
How is performance anxiety successfully treated?
Beta blockers
What is systemic desensitization?
Systemic desensitization is the gradual exposure of a patient to the feared object or situation while teaching relaxation and breathing techniques