Anxiety/depression Flashcards

1
Q

Anxiety DSM V

A
three of six x 6 months 
restless 
feeling on edge 
fatigued 
irritable 
muscle tension 
sleep disturbance
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2
Q

Depression DSM V

A
5 of following most of day nearly every day for a minimum of two weeks 
Sleep 
Interest 
Guilt 
Energy 
Concentation 
Appetite 
Psychomotor 
Suicide
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3
Q

Anxiety evaluation tool

mneumonic

A
GAD 7
MR FISC 
Motor tension 
Restless 
Fatigue 
Irritability 
Sleep disturbance 
Concentration diff.
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4
Q

Depression screening tools

A

PHQ2 or 9

Geriatric depression scale 2 points = positive

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5
Q

SSRI SE

A
GI upset 
sexual dysfunction 
nervousness 
HA 
dry mouth 
sleepiness 
weight gain 
hyponatremia
SIADH (Cr and Na)
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6
Q

SSRI list

A

celexa lexapro

prozac paxil zoloft

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7
Q

Celexa considerations

A

qt prolongation

beers list

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8
Q

Prozac
long____
only FDA approved drug for ____
other_____

A

long half life
only FDA approved antidep for children
on beers list

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9
Q

Paxil
targets _____ and ______
significant_______
se:

A

targets panic and anxiety
significant discontinuation syndrome
se: weight gain

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10
Q

Zoloft
targets ____ and _____
SE:

A

targets anxiety and mild OCD

SE: GI upset, HA

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11
Q

SNRI drugs

A

venlafaxine

cymbalta

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12
Q

Venlafaxine considerations
it can be ____
significant______
monitor for _____

A

energizing
significant discontinuation syndrome
monitor for htn

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13
Q

Cymbalta considerations
significant _____
also indicated for______

A

significant discontinuation syndrome

also indicated for pain

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14
Q

NDRIs

A

wellbutrin

remeron

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15
Q

Wellbutrin SE

caution:

A

nervousness
HA
insomnia
caution: lowers seizure threshold

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16
Q

TCAs

A

trazodone

elavil

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17
Q

Trazodone SE:

A

cardiac and anticholinergic

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18
Q

elavil

indicated for

A

pain and insomnia

beers list

19
Q

Mood stabilizers

A

tegretol
depakote
lithium
lamictal

20
Q

Tegretol
Therapeutic level
renal dosing?

A

therapeutic level: 4-12

renal dosing

21
Q
Depakote 
therapeutic level 
renal dosing? 
liver? 
monitor?
A

50-125
no renal dosing
hepatic caution
monitor cbc- plts, lfts

22
Q

aricept se

A

gi upset

23
Q

lamictal considerations
monitor:
refer:

A

Cr

optho

24
Q

Benzos

A

beer list

25
Q

Benzos
longer half life
shorter half life and considerations

A

longer half life: klonopin, valium (less rebound anxiety, avoid more SE)

shorter: ativan, xanax (harder withdrawal)

26
Q

Other anxiety agents

A

buspar
neurontin
clonidine

27
Q
atypical antipsychotics 
\_\_\_\_ line tx 
treat \_\_\_\_\_\_ sx
SE:
drugs:
A

1st line treatment
treat + and - sx
SE: metabolic syndrome (DM, hypercholesterol, prolactin)
drugs: clozapine, quetipaine, olanzepine, risperdal, geodon, abilify

28
Q

atypical antipsychotics function as

A

serotonin-doparmine antagonists

29
Q

clozapine monitor

A

WBC weekly x 6 months then monthly

30
Q

zyprexa

A

same as seroquel + hyperlipidemia elevated glucose

31
Q

risperdal

A

higher doses EPS
rigidity tremors
elevated prolactin

32
Q

Geodan

A

sedation, dizziness, prolonged QT

take with food

33
Q

abilify
for:
SE:

A

for agitation insomnia
SE: somnolence, akathesia (motor restlessness), weight gain, elevated lipids
(treatment resistant depression)

34
Q

typical antipsychotics
high potency
low potency

A

high potency: haldol, prolixin, trilafon, stelazine, navane

low-potency: thorazine, melleril

35
Q

SE typical antipsychotics

A

SE: ortho hypo, dry mouth, blurred vision, constipation, urinary retention, weight gain, lowering seizure threshold, photosensitivity, tremor, rigidity, agitation, delirium

36
Q

hi potency antipsychotics
risk of eps?
sedation/anticholinergic?

A

haldol, prolixin, trilafon, stelazine, navane
high risk eps
less sedation

37
Q

low potency antipsychotics
risk of eps?
sedation/anticholinergic?

A

thorazine, melleril
low risk eps
higher sedation/anticholinergic

38
Q

EPS types

A
akathesia 
akinesia 
dystonia 
pseudo-parkinsons 
tardive dyskinesia
39
Q

akathesia

A

motor restlessness

40
Q

akinesia

A

absence of movement

41
Q

dystonia

A

muscle spasm

42
Q

pseudo parkinsons

A

shuffling gait, motor slowing, mask like, pill rolling, tremor, muscle rigidity

43
Q

tardive dyskinesia

A

involuntary movement
mouth tongue face jaw trunk
irreversible

44
Q
Treatment EPS
-
-
-
-
-
-
A
anticholinergic- cogentin, artane 
antihistamines- benadryl 
dopamine agonists- amantadine 
benzodiazepines- ativan, klonopin 
beta blocker- propanolol 
alpha 2 agonist- clonidine