Anxiety/depression

Question 1

Anxiety DSM V

Answer 1

three of six x 6 months 
restless 
feeling on edge 
fatigued 
irritable 
muscle tension 
sleep disturbance

Question 2

Depression DSM V

Answer 2

5 of following most of day nearly every day for a minimum of two weeks 
Sleep 
Interest 
Guilt 
Energy 
Concentation 
Appetite 
Psychomotor 
Suicide

Question 3

Anxiety evaluation tool

mneumonic

Answer 3

GAD 7
MR FISC 
Motor tension 
Restless 
Fatigue 
Irritability 
Sleep disturbance 
Concentration diff.

Question 4

Depression screening tools

Answer 4

PHQ2 or 9

Geriatric depression scale 2 points = positive

Question 5

SSRI SE

Answer 5

GI upset 
sexual dysfunction 
nervousness 
HA 
dry mouth 
sleepiness 
weight gain 
hyponatremia
SIADH (Cr and Na)

Question 6

SSRI list

Answer 6

celexa lexapro

prozac paxil zoloft

Question 7

Celexa considerations

Answer 7

qt prolongation

beers list

Question 8

Prozac
long____
only FDA approved drug for ____
other_____

Answer 8

long half life
only FDA approved antidep for children
on beers list

Question 9

Paxil
targets _____ and ______
significant_______
se:

Answer 9

targets panic and anxiety
significant discontinuation syndrome
se: weight gain

Question 10

Zoloft
targets ____ and _____
SE:

Answer 10

targets anxiety and mild OCD

SE: GI upset, HA

Question 11

SNRI drugs

Answer 11

venlafaxine

cymbalta

Question 12

Venlafaxine considerations
it can be ____
significant______
monitor for _____

Answer 12

energizing
significant discontinuation syndrome
monitor for htn

Question 13

Cymbalta considerations
significant _____
also indicated for______

Answer 13

significant discontinuation syndrome

also indicated for pain

Question 14

NDRIs

Answer 14

wellbutrin

remeron

Question 15

Wellbutrin SE

caution:

Answer 15

nervousness
HA
insomnia
caution: lowers seizure threshold

Question 16

TCAs

Answer 16

trazodone

elavil

Question 17

Trazodone SE:

Answer 17

cardiac and anticholinergic

Question 18

elavil

indicated for

Answer 18

pain and insomnia

beers list

Question 19

Mood stabilizers

Answer 19

tegretol
depakote
lithium
lamictal

Question 20

Tegretol
Therapeutic level
renal dosing?

Answer 20

therapeutic level: 4-12

renal dosing

Question 21

Depakote 
therapeutic level 
renal dosing? 
liver? 
monitor?

Answer 21

50-125
no renal dosing
hepatic caution
monitor cbc- plts, lfts

Question 22

aricept se

Answer 22

gi upset

Question 23

lamictal considerations
monitor:
refer:

Answer 23

Cr

optho

Question 24

Benzos

Answer 24

beer list

Question 25

Benzos longer half life shorter half life and considerations

Answer 25

longer half life: klonopin, valium (less rebound anxiety, avoid more SE) shorter: ativan, xanax (harder withdrawal)

Question 26

Other anxiety agents

Answer 26

buspar neurontin clonidine

Question 27

``` atypical antipsychotics ____ line tx treat ______ sx SE: drugs: ```

Answer 27

1st line treatment treat + and - sx SE: metabolic syndrome (DM, hypercholesterol, prolactin) drugs: clozapine, quetipaine, olanzepine, risperdal, geodon, abilify

Question 28

atypical antipsychotics function as

Answer 28

serotonin-doparmine antagonists

Question 29

clozapine monitor

Answer 29

WBC weekly x 6 months then monthly

Question 30

zyprexa

Answer 30

same as seroquel + hyperlipidemia elevated glucose

Question 31

risperdal

Answer 31

higher doses EPS rigidity tremors elevated prolactin

Question 32

Geodan

Answer 32

sedation, dizziness, prolonged QT | take with food

Question 33

abilify for: SE:

Answer 33

for agitation insomnia SE: somnolence, akathesia (motor restlessness), weight gain, elevated lipids (treatment resistant depression)

Question 34

typical antipsychotics high potency low potency

Answer 34

high potency: haldol, prolixin, trilafon, stelazine, navane | low-potency: thorazine, melleril

Question 35

SE typical antipsychotics

Answer 35

SE: ortho hypo, dry mouth, blurred vision, constipation, urinary retention, weight gain, lowering seizure threshold, photosensitivity, tremor, rigidity, agitation, delirium

Question 36

hi potency antipsychotics risk of eps? sedation/anticholinergic?

Answer 36

haldol, prolixin, trilafon, stelazine, navane high risk eps less sedation

Question 37

low potency antipsychotics risk of eps? sedation/anticholinergic?

Answer 37

thorazine, melleril low risk eps higher sedation/anticholinergic

Question 38

EPS types

Answer 38

``` akathesia akinesia dystonia pseudo-parkinsons tardive dyskinesia ```

Question 39

akathesia

Answer 39

motor restlessness

Question 40

akinesia

Answer 40

absence of movement

Question 41

dystonia

Answer 41

muscle spasm

Question 42

pseudo parkinsons

Answer 42

shuffling gait, motor slowing, mask like, pill rolling, tremor, muscle rigidity

Question 43

tardive dyskinesia

Answer 43

involuntary movement mouth tongue face jaw trunk irreversible

Question 44

``` Treatment EPS - - - - - - ```

Answer 44

``` anticholinergic- cogentin, artane antihistamines- benadryl dopamine agonists- amantadine benzodiazepines- ativan, klonopin beta blocker- propanolol alpha 2 agonist- clonidine ```