Antivirals in Hep C

Question 1

What is a Hep C cure called?

Answer 1

Sustained virulogic response

Question 2

What is a chronic side effect of curing Hep C?

Answer 2

Positive anti-body

Question 3

Sofosbuvir

Answer 3

Pangenotypic

Well tolerated

Question 4

Ledipasvir / sofosbuvir

Answer 4

Harvoni
PPI and acidity
$1300 per day
12-24 wk treatment

Question 5

Daclatasvir

Answer 5

Pangenotypic
Newest
12 week treatment

Question 6

Elbasvir / grazoprevir

Answer 6

Zepatier
GT 1 on dialysis
GT 4

Question 7

Sofosbuvir / velpatasvir

Answer 7

Exclusive
12 weeks
12 weeks w/ ribavirin w/ bad liver

Question 8

Sofosbuvir / velpatasvir / Voxilaprivir

Answer 8

Voservi
2nd line treatment when:
Prior NS5A inhibitor use
Prior SOF use

Question 9

Glecaprivir / Pibrentasvir

Answer 9

Mavyret
8 week Rx
Can be 12 or 16 w/ complicated disease

Question 10

Ribavirin

Answer 10

Used w/ interferon or voservi
PGY cat X. Safe sex for 6 mos post Rx
Never give iron w/ hemolytic anemia!!!