Antivirals Flashcards

1
Q

Give some complications of influenza.

A
Bronchitis
Pneumonia
Sinusitis
Acute otitis media
Croup
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2
Q

Name two M2 ion channel inhibitors.

Name 3 limitations to their usage.

A

Influenza A only

CNS and renal side effects

M2 gene is prone to mutations commonly and therefore rapid emergence of resistance occurs.

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3
Q

Name two neuraminidase inhibitors.

What is the difference in their route of administration?

Renal excretion?

Which one has is not as effective against H1N1?

A

Oseltamivir
Zanamavir

Oseltamivir is pill (PO) whereas zanamivir is dry aerosol powder.

Zanamivir

Oseltamivir

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4
Q

Where are HHV 5 6 and 7 latent in?

A

Lymphoreticular
Secretory glands
Kidney cells

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5
Q

Which virus is associated with Kaposi’s sarcoma?

A

HHV-8

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6
Q

What complications are HHV 6 and 7 associated with?

A

Meningoencephalitis

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