Antivirals Flashcards
Aciclovir is what type of drug?
Anti Herpes virus
Famiciclovir and Valaciclovir are what?
Similar drugs to Aciclovir, oral admin
What is Aciclovir used for?
Treatment of HSV and VZV
Describe Foscarnet and its use
Non-nucleoside analogue herpes virus drug.
Used to treat analogue resistant HSV, VZV and CMV
Ganciclovir is used for what?
Treatment of serious CMV infection, usually in immunocomp. patients.
What kind of drug is Ganciclovir?
Nucleoside analogue, used for treatment of serious CMV
Topical Aciclovir is used for treatment of what?
Coldsore type HSV infection
Name the three main anti-HIV drugs
AZT (zivovudine), Saquinavir, nevirapine
What is the mech. of action of AZT
inhibits viral reverse transcriptase
All antivirals are…
virustatic
Lamivudine can be used to treat?
Hep B and has efficacy against HIV
What is the main drug for Hepatitis B/C treatment
Pegylated Interferon a.
How is Interferon PEG administered and what are it’s effects?
Subcutaneous injection. Treatment of Hep B/C. serious side effects.
What type of drug is Lamivudine?
Nucleoside analogue for Hep B/C treatment and HIV
Oseltamivir and Zanamivir are used to treat…
Influenza A and B
What type of drug is Ribavarin and what is it’s use?
Nucleoside analogue, treatment of severe Respiratory Syncytial Virus
What is the application of Cidofovir?
Treatment of CMV retinitis when other herpes virus drugs cannot be used
What is Ganciclovir used to treat and what are its side effects?
Sever CMV, usually in immunocomp. patients. Can cause bone marrow deficiency.
Describe the use of ribivarin?
Treatment of severe Respiratory Syncytial Virus infections. Nucleoside analogue, admin by mist spray into lungs.
Anti herpes virus are effective when…
Started early in infection.
Anti-Herpes virus drugs generally have…
renal and hepatotoxicity
