Antivirals Flashcards
1
Q
Tx for Herpes (most types)
A
Aciclovir:
Guanosine analogue, blocks viral DNA extension.
(CMV doesn’t have the thymidine kinase so it doesn’t work.)
2
Q
Tx for CMV
A
Ganciclovir.
SFX: BM suppression.
2nd: Foscarnet.
3rd: Cidofovir for retinitis.
3
Q
Antivirals for Influenza
A
Amantadine (A only) (H1N1 now resistant).
NA inh: Oseltamavir, Zanamivir, Sialic acid.
4
Q
Tx for Hep B
A
Pegylated interferon alpha 2a,
Entecavir, (viral Pol inh)
Tenofovir (RTI).
5
Q
Tx for Hep C
A
Peglyated interferon alpha 2b,
Ribavirin (RNA nu analogue; haemolytic anaemia)
