Antivirals

Question 1

what is the combo of tenofovir and emtricitabine used for

Answer 1

pre exposure prophylaxispost exposure prophylaxis

Question 2

what are some adverse effect of emtricibabine

Answer 2

hyperpigmentation of the palms and skin discoloration

Question 3

what are the adverse effects with Zidovudine

Answer 3

bone marrow supression

Question 4

what are special consideration for lamivudine

Answer 4

Epirvir HBVresistance is quite common

Question 5

What is truvada

Answer 5

emtricitabine and tenofovir1 tab PO dialy

Question 6

what is atripla

Answer 6

emtricitabine, tenofovir, efavirenz1 tab PO daily

Question 7

What is stribild

Answer 7

emtracitabine, tenofivir, elvitegravir, cobivistat1 tab PO dialy

Question 8

What is dosing like for efaviranz

Answer 8

600mg PO at bed time

Question 9

How should you take efaviranz

Answer 9

empty stomach

Question 10

what are the averse effects with Efaviranz

Answer 10

CNS effectsstops after 2-4 wksrashincreased LFTTeratogenfalse positive weed test

Question 11

what is rilpivirine not used for and what should you avoid using it with?

Answer 11

high viral loadsProton pump inhibitors

Question 12

what are some adverse effects with Nevirapine

Answer 12

hepatits and fetal hepatic necrosis

Question 13

What are the special considerations with Atazanavir and what are the adverse effects

Answer 13

avoid with proton pump inhibtorsindirect hyperbiliruninemialack of effects on lipids

Question 14

what is a special precautions with Darunavir

Answer 14

caution with sulfa allergyRash

Question 15

what are the adverse effects with Raltegravir& Stribild

Answer 15

increased creatine kinase

Question 16

when do antivirals need to be administered for HSV and VZV

Answer 16

Acyclovir48-72hr with onset of rash

Question 17

what is the blackbox warning with Ganciclovirwhat are the special considerations

Answer 17

treats CMVbone marrow toxHydrate aggressivelymonitor renal functionavoid skin contact alkaline and teratogenic

Question 18

what is the the drug of choice for Tx and Px of CMV

Answer 18

Valganciclovir

Question 19

what are the special considerations with Valganciclovir

Answer 19

PO onlylook alike sound alike with Valcyclovir and Valganciclovir

Question 20

what is the adverse effect with Foscarnet what does it treat

Answer 20

treat CMVhighly nephrotoxic

Question 21

what agents are used to treat Hep B virus infection

Answer 21

Adefovir, Lamivudine, entecavir, telbivudine, tenofovirinterferon alfa

Question 22

What are the adverse effects with Entecavir

Answer 22

dizziness and fatigue

Question 23

what are the adverse effects of interferon for HVC infection

Answer 23

flu-like syndromeH/A, myalgia, arthralgias, fatigue, malaise, fever, chills,improves as treatment continues

Question 24

what are the special considerations with interferons for HVC

Answer 24

contraindication to therapyhepatic deompensationautoimmune diseasehistory of arrhythmiapregnancy

Question 25

what are the adverse effects with ribavirin

Answer 25

used for HCVhemolytic anemiateratogeniccan't handle cansules if prego.

Question 26

what are the special consideration with sofosbuvir

Answer 26

Used for HVC$1,000 per tabpan genotypic activitymake it possible to treat some pts with out interferon

Question 27

how is simeprivir takenwhat are special consideration of simeprevir

Answer 27

used for HCVwith foodassessment of Q80K mutationdrug interactions

Question 28

what is the best method of routine prevention

Answer 28

inactivated influenza vaccine

Question 29

what are the adverse effects with amantadine

Answer 29

CNS tox increase with elderly

Question 30

what amantadine use to treat now

Answer 30

no longer used to treat influenza prophylaxisused to treat parkinsons disease and drug induced EPS

Question 31

Rimantadine adverse effects

Answer 31

less CNS adverse effects

Question 32

what can actually happen to disinfectant and antispectic

Answer 32

they may become contaminated with spore or bacteria and transmit infection