Antiviral Vaccines Flashcards
1
Q
Advantages of live attenuated
A
No adjuvant
Strong immune response
Single dose
Both humoral and cell-mediated immunity
Life long Immunity
2
Q
Disadvantages of live attenuated
A
Reversion to virulence possible
Immunocompromised → in danger
Less stable
Contamination problems
Contraindicated in pregnancy
3
Q
Advantages of killed vaccine
A
Safer → no pathology
Greater stability
4
Q
Disadvantages of killed vaccine
A
More cost
Booster dose
Not long lived
May not work
5
Q
Advantages and disadvantages of subunit vaccine
A
Advantage → No disease, safer, stable
Disadvantage → Not effective, short lasting, Hypersensitive
6
Q
DNA vaccine advantage and disadvantage
A
Advantages → Both humoral and cell-mediated, wider range, stable, can be designed
Disadvantages →safety, Not very effective…?
