Antiviral

Question 1

Which Toll-like receptor does the imiquimod compound (imidazoquinoline) bind to within APCs to cause release of cytokines and thereby stimulate the immune system?

Answer 1

TLR7/8

Question 2

Wich cytokines does the imiquimod stimulate?

Answer 2

TNF- alpha, INF- gamma, IFN-alpha, IL-1, IL-6, IL-8, IL-12, GM-CSF, G-CSF

Question 3

Moa of famcyclovir, ganacyclovir and cidofovir

Answer 3