Antiseptics and disinfectants Flashcards
What is the clinical use of Permethrin?
kills lice
What is the MOA of Permethrin?
disrupts nerve signaling, causing paralysis - acts on Na+ channels
What is the clinical use of Malathion?
lice infestations
_____ are used on live tissue (cleansing of initial wound, used rarely for established local infections)
antiseptics
____ is complete destruction of microorganisms, while ____ is reduction to public health standard levels
sterilization; sanitation
What is the MOA of ethanol and isopropanol?
precipitates bacterial proteins and dissolves membranes
What is the MOA of aldehydes?
crosslinking and precipitating proteins
This aldehyde is a disinfectant; 2-4 days for killing spores; more volatile that glutaraldehyde
formaldehyde
What is the MOA of the topical antiseptic Oxychlorosense sodium?
hypochlorous acid release
This phenol is bacteriastatic gram positive only, encourages gram negative growth, and if absorbed through skin, can cause CNS stimulation
hexachorophene
What is the MOA of hydrogen peroxide?
hydroxy free radical
What enzyme in the body neutralizes hydrogen peroxide quickly?
catalase
