Antiseizure Medications Flashcards
What are the drugs of choice for Grand mal [tonic-clonic]
valproate, lamotrigine, levetiracetam
What are the drugs of choice for Petit mal [absence]
ethosuximide, valproic acid
What are the drugs of choice for Partial
carbamazepine, lamotrigine, levetiracetam
What are the drugs of choice for Status epilepticus
benzodiazepines: diazepam-lorazepam-midazolam
Valproate
General mechanisms of action (cellular target):
Side effects:
Use in pregnancy:
Lamotrigine
General mechanisms of action (cellular target):
Side effects:
Use in pregnancy:
Levetiracetam
General mechanisms of action (cellular target):
Side effects:
Use in pregnancy:
Ethosuximide,
General mechanisms of action (cellular target):
Side effects:
Use in pregnancy:
Valproic acid
General mechanisms of action (cellular target):
Side effects:
Use in pregnancy:
Carbamazepine
General mechanisms of action (cellular target):
Side effects:
Use in pregnancy:
Lamotrigine
General mechanisms of action (cellular target):
Side effects:
Use in pregnancy:
Benzodiazepines
General mechanisms of action (cellular target):
Side effects:
Use in pregnancy:
Relate the postulated mechanisms underlying seizure pathophysiology for simple and complex partial, absence, tonic-clonic, and status epilepticus seizure disorders to the mechanisms of actions of the drugs of choice for their treatment. Focus on neurotransmitter systems and ion channels as drug targets.
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