Antipsychotics: FGAs Flashcards

1
Q

common uses of FGAs

A

schizophrenia
agitation/aggression
nausea & vomiting
intractable hiccups

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2
Q

FGAs to know

A

Haloperidol

Chlorpromazine

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3
Q

What are the mental disorders

A
  1. distress
  2. danger
  3. deviant
  4. dysfunction
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4
Q

what are some positive symptoms of schizophrenia

A

hallucinations
delusions
disorganized speech
bizarre behavior

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5
Q

negative symptoms of schizophrenia

A

affective flattering
alogia- not sitting just sitting
avoliton- no drive
social isolation

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6
Q

How do FGAs work?

A

block dopamine receptors in the brain since there is to much.

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7
Q

dopamine pathways and which one do we want the medication to go to and what do they do

A

Mesolimbic- we want the medication here/ decrease positive symptoms of schizophrenia
mesocortical- make negative symptoms worse
nigrostriatal-
tuberionfundibular- endocrine problems such as gynecomastia

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8
Q

major side effects

A
anticholinergic effects
orthostatic hypotension
sedation
neuroendocrine effects
photosensitivity
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9
Q

extrapyramidal symptoms

A

acute dystonia
akathisia
parkinsonism
tardive dyskinesia

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10
Q

Neuroleptic Malignant syndrome

A
F- fever
E- elevated WBCs and CPK
V- vitals signs unstable
E- encephalopathy
R- rigidity ( lead pipe)
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11
Q

what does a brand new nurse need to know about FGAs

A
work by blocking dopamine
have lots of serious side effects
notorious for causing EPS
Don't treat EPS with antipsychotic 
know the signs and symptoms of NMS
watch out for orthostatic hypotension
wear sunscreen
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12
Q

common uses of SGAs

A

Schizophrenia
bipolar disorder
dementia with psychotic features

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13
Q

SGAs to know

A

clozapine
risperidone
olanzapine
aripiprazole

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14
Q

how do SGAs work?

A

block dopamine and serotonin receptors in the brain

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15
Q

Comparison to FGAs

A

lower risk of EPS
Really high risk of metabolic syndrome
super expensive
probably equally effective

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16
Q

metabolic syndrome signs and symptoms

A
central obesity
hypertension
higher blood sugar
dyslipidemia 
leads to diabetes
17
Q

What does a new nurse need to know about SGAs

A

lower risk of EPS
high risk for metabolic syndrome
watch for signs of infection if a client is taking clozapine
watch for signs of neuroleptic malignant syndrome

18
Q

is clozapine effective?
what can it cause?
what does it require?

A

yes
agranulocytosis
weekly WBC monitoring