Antipsychotics: FGAs Flashcards
common uses of FGAs
schizophrenia
agitation/aggression
nausea & vomiting
intractable hiccups
FGAs to know
Haloperidol
Chlorpromazine
What are the mental disorders
- distress
- danger
- deviant
- dysfunction
what are some positive symptoms of schizophrenia
hallucinations
delusions
disorganized speech
bizarre behavior
negative symptoms of schizophrenia
affective flattering
alogia- not sitting just sitting
avoliton- no drive
social isolation
How do FGAs work?
block dopamine receptors in the brain since there is to much.
dopamine pathways and which one do we want the medication to go to and what do they do
Mesolimbic- we want the medication here/ decrease positive symptoms of schizophrenia
mesocortical- make negative symptoms worse
nigrostriatal-
tuberionfundibular- endocrine problems such as gynecomastia
major side effects
anticholinergic effects orthostatic hypotension sedation neuroendocrine effects photosensitivity
extrapyramidal symptoms
acute dystonia
akathisia
parkinsonism
tardive dyskinesia
Neuroleptic Malignant syndrome
F- fever E- elevated WBCs and CPK V- vitals signs unstable E- encephalopathy R- rigidity ( lead pipe)
what does a brand new nurse need to know about FGAs
work by blocking dopamine have lots of serious side effects notorious for causing EPS Don't treat EPS with antipsychotic know the signs and symptoms of NMS watch out for orthostatic hypotension wear sunscreen
common uses of SGAs
Schizophrenia
bipolar disorder
dementia with psychotic features
SGAs to know
clozapine
risperidone
olanzapine
aripiprazole
how do SGAs work?
block dopamine and serotonin receptors in the brain
Comparison to FGAs
lower risk of EPS
Really high risk of metabolic syndrome
super expensive
probably equally effective