Antipsychotics Flashcards
Haloperidol: Class
First generation antipsychotic
Haloperidol: MOA
D2 antagonist
Alpha1 inhibition
Haloperidol: indication
Psychotic sxs
Haloperidol: side effects
Long QT
EPS
TD
Haloperidol: contraindication
Parkinson’s
CNS depression
CVD
Haloperidol more commonly causes TD in what population?
The elderly
Do you keep the Pt on Haloperidol forever?
Attempt dose reduction on a scheduled basis.
Risperdone: class
Second generation antipsychotic
Risperdone: MOA
5HT and D antagonism
Mild A1, A1, H1 antagonism
Risperdone: indication
psychosis (positive and negative sxs)
mania
Risperdone: contraindications
Parkinson’s
Seizure Hx
Attempt Risperdone _____ _____ on a scheduled basis
dose reduction
Seroquel: class
Second generation antipsychotic
Seroquel: MOA
5HT and D antagnonism
Seroquel: indication
Bipolar
Schizophrenia
Adjunct med in MDD
Seroquel: dosing and effect
50mg - hypnotic
300mg - antidepressive
400-800mg - antipsychotic
Seroquil: black box warning
SI
Seroquil and the elderly….
Beers list
Latuda: class
Second generation antipsychotic
Latuda: indication
Schizophrenia
Bipolar
How should Latuda be taken?
With at least 350 calories worth of food
A few other things to know about Latuda…
Black box warning
Beers list
Geodon: class
Second generation antipsychotic
Geodon: indication
Bipolar
Schizophrenia
Acute agitation in schizophrenia
Geodon: side effects
SJS, EPS
How should Geodon be taken?
With at least 500 calories worth of food
A few other things about Geodon…
Black box warning
Beers list
There are more second generation antipsychotics. Let’s just name them all…
Risperidone Seroquel Zyprexa Clozapine Abilify Latuda Geodon