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Pharmacology > Antiprotozoal and antihelminthic drugs > Flashcards

Antiprotozoal and antihelminthic drugs Flashcards

1
Q

Amebiasis- luminal form

A

Diloxanide
Paromomycin
Etofamid
Iodoquinol

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2
Q

Amebiasis - invasive

A

Metronidazole ( tinidazole , ornidazole)

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3
Q

Amebiasis- reserve drugs

A

Chloroquine

Dehydroemetine

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4
Q

Giardiasis

A

Metronidazole
Nitazaxanide
Albendazole

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5
Q

Trichomoniasis

A

Metronidazole
Tinidazole
Ornidazole

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6
Q

Toxoplasmosis

A

Pyrimethamine with sulfonamides- - (sulfadiazine, cotrimoxazole) or macrolide (spiramycin)

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7
Q

Leishmaniasis

A

Visceral- sodium stibogluconate
Meglumine antimonate
Or pentamidine, amphotericin B

Cutaneous— paromomycin
Meglumine antimonate

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8
Q

Schistosomiasis

A

Metrifonate

Oxamniquine

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9
Q

Trypanosomiasis- american

A

“Chagas disease”

- Nifurtimox

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10
Q

African trypanosomiasis

A

“Sleeping sickness”
Suramin
Efornithine
Melarsoprol

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11
Q

Balantidiasis

A

Tetracycline

Metronidazole

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12
Q

Antimalarial drugs- 1) blood schizontocides

A 
Quinine
Quinidine
Chloroquine
Sulfadoxine / pyrimethamine
Mefloquine
Artesunate 
Artemether 
Dihydroartemisinine
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13
Q

Anti malarial- tissue schizontocides

A

Primaquine

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14
Q

Chemoprophylaxis of malaria- individual

A

Chloroquine
Mefloquine
Doxycycline

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15
Q

Chemoprophylaxis of malaria - social

A

Gametocides drugs -
Chloroquine
Primaquine
Quinocide

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16
Q

Intestinal nematodes

A 
Albendazole
Mebendazole
Pyrantel
Levamisole
Thiabendazole
Piperazine
Pirviny paniya
17
Q

Extra-intestinal nematodes

A

Mebendazole
Ivermectin
Diethylcarbamazine

18
Q

Cestodiasis

A

Praziquantel
Niclosamide
Albendazole
Mebendazole

19
Q
  • clonorchiasis
  • opistorhosis
  • schistosomiasis
  • paragonimiasis
A

Praziquantel

20
Q

Fascioliasis

A

Triclabendazole

Bithionol

21
Q

Trematodiasis

A

Together with drugs for treatment of extra-intestinal nematodes constitute group of drugs for treatment of helminthic infections

22
Q

MAO: piperazine and ivermectin

A

Open the helminthic cl- channels –>

hyper polarization and relaxation of parasite muscles

23
Q

MOA: praziquantel

A

Influx of ca2+ ions —>

Spams of the muscle of parasite

24
Q

MOA: pyrantel pamoate levomisole

A

Hyper stimulation of the para’s nicotinic receptor —> paralysis of helminth muscle

25
Q

MOA: diethylcarbamazine

A
  • microfilaria immobilization

- impairment of surface structures

Pharmacology (3 decks)

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