Antiplatelet drugs Flashcards
Aspirin MOA ROA Indications Adverse
MOA
COX inhibitor
ROA
Oral
Indications
ACS, stroke, arterial thrombosis
Adverse:
Bleeding, Gastric Irritation
Clopidogrel
MOA
ADP receptor inhibitor
ROA
oral
INdications
ACS, Stroke, in stent thrombosis
Adverse:
- Bleeding
- TTP
Prasugrel/Ticagrelor
MOA
ADP receptor inhibitor
ROA
oral
Indications
ACS, Stroke, in stent thrombosis
Adverse:
1. Bleeding
NSAIDs
MOA
COX inhibitor
ROA
oral
Indications
various diseases
Adverse:
Bleeding
Dipyridamole
MOA
Phosphodiesterase Inhibitor
ROA
oral
Indications:
stroke, arterial thrombosis
Adverse:
Bleeding
Cilostazol
MOA
Phosphodiesterase inhibitor
ROA
oral
Indications:
Intermittent claudication
Adverse:
Hypotension
Abciximab/ Eptifibatide/ Tirofiban
MOA
GP 2b/3a inhibitor
ROA:
Intravenous
Indications:
ACS/PCI (percutaneous coronary intervention)
Adverse:
Bleeding
Monteleukast
MOA
Leukotriene receptor inhibitor
ROA
oral
Indications
Allergic reactions
Adverse:
Hypotension
Behavioral changes
Zafirleukast
MOA
Leukotriene receptor inhibitor
ROA
oral
Indications
Asthma
Adverse
Hypotension
Zieuton
MOA
Lipoxygenase Inhibitor
ROA
oral
Indication
Asthma
Adverse
Hypotension