Antiplatelet Agents

Question 1

Antiplatelet Agents Drug Names

Answer 1

Aspirin 
Clopidogrel
Dipyridamole
Epitifibatide
Ticargrelor

Question 2

Antiplatelet Agents Therapeutic Actions

Answer 2

• Blocks the receptor site on the platelet membrane which prevents platelets from sticking together and clumping

Question 3

Antiplatelet Agents Indications

Answer 3

• CV disease that are prone to clogged vessels
• Keep grafts open/ patent
• Prevent cerebrovascular occlusion (strokes and TIAs)
• Adjuncts to thrombolytic therapy after MI and to prevent another MI
• Aspirin: Anti-inflammatory, analgesic, and antipyretic effects

• More effective against arterial thrombosis

Question 4

Antiplatelet Agents Contraindications and Cautions

Answer 4

Contraindication:
• Allergy
• Pregnancy/ lactation

Caution:
• Bleeding disorder
• Recent surgery
• Closed-head trauma

Question 5

Antiplatelet Agents DDI

Answer 5

DDI:
• Another drug that effects blood clotting
• CYP3A inhibitors or inducers

Question 6

Antiplatelet Agents Adverse Effects

Answer 6

• Bleeding disorder
• CNS: Headache, dizziness, and weakness
• GI distress

Question 7

Antiplatelet Agents:

Assessment

Answer 7

Assess:
Hx: allergy, Pregnancy and lactation, known bleeding disorder, recent surgery, or closed head injury
Physical: vital signs, weight, heart & lung sounds, skin, perfusion(pulses) (baseline)
Labs: Clotting studies

Question 8

Antiplatelet Agents:

Diagnosis

Answer 8

Dx:

• Acute pain
• Risk for injury
• Deficient knowledge

Question 9

Antiplatelet Agents:

Implementation

Answer 9

Implementation:
• Provide small, frequent meals
• Safety measurers
• Provide increased precautions against bleeding during invasive procedures
• Mark the chart of any patient receiving this drug
• Provide thorough patient teaching

Question 10

Antiplatelet Agents:

Evaluation

Answer 10

Eval:
Response to the drug
Adverse effects 
Effectiveness of comfort measures Compliance with the regimen
Effectiveness of the teaching plan