Antiphospholipid Syndrome

Question 1

autoantibody-mediated acquired thrombophilia characterized by recurrent arterial or venous thrombosis and/or pregnancy morbidity

Answer 1

Antiphospholipid syndrome

Question 2

consists of a mottled reticular vascular pattern that appears as a lace-like, purplish discoloration of the skin.

Answer 2

Livedo reticularis

Question 3

Target INR in APAS patients on warfarin

Answer 3

2.5 to 3.5

Alone or in combination with aspirin 80mg OD

Question 4

Administered to prevent pregnancy morbidity in APS patients

Answer 4

LMWH with aspirin 80mg OD

Question 5

Given when glucocorticoids are ineffective.

Answer 5

IV immunoglobulin (IV Ig) 400mg/kg OD x 5 days