Antiparasitics Flashcards
Parasiticide
Kills or inhibits internal and/or external parasites
poison that is more toxic to the parasite than the host.
Margin of safety will vary, depending on the truck.
Parasiticide categories
Anthelminctics
Amebicides
Insecticides
Anthelminctics
Kills helminthes
Ex. Nematodes, cestodes
Amebicides
Kills Protoza
Ex. Coccidia
Insecticides
Kills arthopods
Ex. Ticks , lice , etc..
Considerations with antiparasitics
Continual reinfestation occurs - drugs are temporary.
Parasites may develop immunity - efficiency? necessity?
treatment may occur too late - internal damage
stay up-to-date on new drugs.
Considerations with antiparasitics
Continual reinfestation occurs - drugs are temporary.
Parasites may develop immunity - efficiency? necessity?
treatment may occur too late - internal damage
stay up-to-date on new drugs.
Poor response
Incorrect drug, dose/administration or timing,
rapid reinfestation
drug resistance
Poor response
Incorrect drug, dose/administration or timing,
rapid reinfestation
drug resistance
Why is it important to read labels?
To make sure it’s labelled for the correct parasite - because each parasiticide is different!
Why is it important to read labels?
To make sure it’s labelled for the correct parasite - because each parasiticide is different!
Avermectins
Most effective - least toxic!
Broad spectrum:
Nematodes (Anthelminctics)
Arthropods (Insecticides) - ectoparasites; lice, mites, ticks
Does NOT kill flukes/tapeworms/protoza (toxoplasma)
Safe.. except..
Murray grey cattle
Collie breeds - ivermectin
Types of avermectins
Ivermectin
Milbemycin oxime
Moxidectin
Doramectin
Eprinomectin - dairy bc 0 WD time
Selamectin
Benzimidazoles
Nematodes (roundworms)
Some cover trematodes(flukes) / cestodes(tapeworm)
Can see vomiting/dirrhea - drontal
Embryotoxicity - DONT USE WHEN PREGO!!
Albendazole - aplastic anemia in dogs/ cats/humans
Tetrahydropyrimidines
NARROW SPECTRUM!
(Mature & some migrating nematodes)
Adverse side effects:
Increase RR, ataxia, profuse sweating
Ascarids (equine) ,
nematodes (equine),
strongyles (equine/bovine/ovine),
Hookworms (feline / canine )
