Antioxidants--Goueli Flashcards
1
Q
Vitamin C deficiency
A
impaired wound healing
bleeding ecchymoses
swollen gums
anemia
enlargement and keratosis of follicles
lethergy
depression
2
Q
Mechanism of reperfusion injury
A
reduced electron carriers overwhelmed when oxygen becomes available from reperfusion
3
Q
Chronic granulometous disease mechanism
A
NADPH oxidase subunit mutation
–> enzyme that doesn’t function properly
*more suceptible to catalase + organisms
4
Q
Catalase mechanism
A
reduces H2O2 to water
*mostly in peroxisomes
*prevents Fenton rxn and Haber-Weiss reaction
5
Q
Superoxide dysmutase mechanism
A
O2- + 2 H+ => H2O2
then later…
H2O2 => 2 H2O + O2