Antimuscarinics - hyoscine butylbromide Flashcards
1
Q
What is the mechanism of action of antimuscarinics?
A
Competitively inhibit ACh - inhibit parasympathetic activation, reducing smooth muscle tone and peristaltic contration in the gut and urinary tract, and reducing secretions from glands in the gut and respiratory tract
2
Q
What are adverse side effects of antimuscarinic drugs?
A
- Tachycardia
- Dry mouth
- Constipation
- Urinary retention in those with BPH
- Blurred vision
- Drowsiness and confusion
3
Q
Why should you be careful using anti-muscarinics in individuals susceptible to acute angle glaucoma?
A
Can precipitate raised intraocular pressure
4
Q
What should you avoid using antimuscarinics in?
A
- Angle closure glaucoma
- Arrythmias
5
Q
What is the brand name for hyocine butylbromide?
A
Buscopan
