Antimicrobial drugs general and specific other than adv effect and MOA

Question 1

Most common mechanism of resistance transfer in bacteria is???

Answer 1

Plasmid by conjugation

Question 2

Mutation causes resistance to how many drugs and plasmid causes resistance to how many drugs???

Answer 2

Mutation - Single drug

Plasmid transfer - Multidrug resistance

Question 3

Protein synthesis inhibitors are???? cidal or static???

Answer 3

Static

Question 4

Most common mechanism of resistance in staphylococcus is by

Answer 4

Penicillinase production

Question 5

Most common mechanism of resistance in staphylococcus to methicillin is by

Answer 5

Altered penicillin binding protein

Question 6

Which classification is by structure of enzyme and which classification is based on substrate of enzymes and its inhibitors???

Answer 6

Amblers (structure of enzyme) and Bush’s (substrate of enzymes and its inhibitors)

Question 7

Which are the safest antimicrobial in renal failure patients???

Answer 7

Cefoperazone and cefpiramide

Question 8

Which tetracyclines can be safely used in renal failure patient???

Answer 8

Tigecycline, Doxycycline and Minocycline

Question 9

Sparfloxacin is the longest or shortest acting fluoroquinolones???

Answer 9

Longest