Adverse effect- mixed part 1 Flashcards
PPI causes hypothyroidism or hyperthyroidism as long term side effect????
It does not cause both.
Enterocutaneous fistula closure is seen with which drug`
Infliximab
What are the side effect of isotretinoin??
Hyperlipidemia , myalgia, arthralgia
Which causes greater haemorrhagic cystitis
Ifosfamide is greater to cyclophosphamide
Drugs causing raynaud’s disease
Blood Cannot Pass in Narrow Blood VesselsBleomycin, Cisplatin ,Ponatinib, Nilotinib, Vinblastine
What are the side effect of L Asparaginase
5H are the side effect HyperglycemiaHyperlipidemia induced pancreatitisHypersensitivity HepatotoxicityHemorrhage or thrombosis
What is the most common cause of SIADH
The most common cause is Vincristine. Cyclophosphamide can also cause SIADH
What are the causes of Hand and foot syndrome
Capecitabine , 5FU Doxorubicin GemcitabineSunitinib, Sorafenib and Pazopanib
Between 5FU and capecitabine which causes maximum Hand and foot syndrome
Ans is Bouncer!!! Capecitabine.
What are the drug causing cardiotoxicity
FAT Cardio 5FUAnthracyclines (Maximum with doxorubicin and daunorubicin)TrastuzumabCyclophosphamide at high doses.
How does 5FU causes cardiotoxicity???
It causes coronary vasospasm and precipitates ischemia.
Radiation recall syndrome
Dactinomycin Doxorubicin Daunorubicin
What are the side effect of chloroquine
BCG LQ Bull eye retinopathyConvulsionG6PD deficient haemolysisLow ocular pressure in eyeQR and T wave abnormality
What does BCG LQ stands for???
These are the side effect of chloroquine. Bull eye retinopathyConvulsionG6PD deficient haemolysisLow ocular pressure in eyeQR and T wave abnormality
Side effect of Ethionamide
ETHIONElevated ALT/ASTTaste changeHypothyroidismImpotenceOcular toxicity Nausea and Vomiting
Side effect of sulphonamides
BIKASH Bone marrow suppression Insoluble in urine crystalluriaKernicterus in newbornAIPAgranulocytosisSJS or would be given as Rash Haemoglobin (which is Met)
Out of sulphonamides side effect mnemonic BIKASH how many are reasoning and how many are direct???
Only 2 is reasoning and 4 are direct. Bone marrow suppression Insoluble in urine crystalluriaKernicterus in newbornAIPAgranulocytosisSJS or would be given as Rash Haemoglobin (which is Met)
SJS side effect of sulfonamide can also be mentioned as???
Rash The other side effect include BIKASH Bone marrow suppression Insoluble in urine crystalluriaKernicterus in newbornAIPAgranulocytosisSJS or would be given as Rash Haemoglobin (which is Met)
Which antitubercular drug causes hepatotoxicity and which cause nephrotoxicity???
HRZ causes hepatotoxicity and E causes nephrotoxicity
HRZ causes hepatotoxicity. Can you grade it???
Z>H>R Pyrazinamide> Isoniazid> Rifampicin
Which ATT crosses the BBB(maximum amount) and is associated with neuropsychiatric symptoms like memory loss , euphoria dnd hallucination as seen in psychosis
Isoniazid
Isoniazid is associated with which neurological adverse effect???
Associated with neuropsychiatric symptoms like memory loss , euphoria dnd hallucination as seen in psychosisMaximum crosses the BBB.
Maximum and minimum peripheral neuropathy is caused by which NRTI drug???
Stavudine (maximum peripheral neuropathy) and Lamivudine (minimum peripheral neuropathy)
What is the order of hemolysis in G6PD deficiency with antimalarials drug
Primaquine > Chloroquine > Quinine
Which causes flaccid paralysis and which cause spastic paralysis in helminthes
Ivermectin piperazine ( flaccid paralysis )Praziquantel metrifonate pyrantel pamoate ( spastic paralysis )
Which causes more photosensitivity??? Demeclocycline or Doxycycline
Demeclocycline
Which the fluoroquinolones with maximum photosensitivity and QT prolongation???
Sparfloxacin
