Antimicrobial Drugs Flashcards
Adverse Effects of
broad spectrum penicillins, cephalosporins
Candida (thrush)
Allergic Reactions (Immediate or Delayed such as rush)
Convulsions, encephalopathy
Adverse Effects tetracyclines
Liver toxicity
Adverse Effects gentamicin, vancomycin
Renal Toxicity
Ototoxicity
Adverse Effects of ethambutol (TB)
Optic neuropathy
Adverse Effects of isoniazid (TB), metronidazole
Peripheral neuropathy
Adverse Effects of co-trimoxazole
Haematological
- marrow toxicity
- megaloblastic anaemia (folate metabolism)
Inhibition of cell wall synthesis
B-Lactams: penicillins and cephalosporins
Glycopeptides: vancomycin, teicoplanin
Inhibition of Protein Synthesis
Aminoglycosides: gentamicin
Macrolides: clarithromycin
Tetracyclines: doxycycline
Oxazolidinones: linezolid
Inhibition of Nucleic acid synthesis
Trimethoprim
Sulfonamides: sulfamethoxazole
Quinolones: ciprofloxacin