Antimicrobial Drugs Flashcards

1
Q

Adverse Effects of

broad spectrum penicillins, cephalosporins

A

Candida (thrush)
Allergic Reactions (Immediate or Delayed such as rush)
Convulsions, encephalopathy

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2
Q

Adverse Effects tetracyclines

A

Liver toxicity

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3
Q

Adverse Effects gentamicin, vancomycin

A

Renal Toxicity

Ototoxicity

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4
Q

Adverse Effects of ethambutol (TB)

A

Optic neuropathy

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5
Q

Adverse Effects of isoniazid (TB), metronidazole

A

Peripheral neuropathy

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6
Q

Adverse Effects of co-trimoxazole

A

Haematological

  • marrow toxicity
  • megaloblastic anaemia (folate metabolism)
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7
Q

Inhibition of cell wall synthesis

A

B-Lactams: penicillins and cephalosporins

Glycopeptides: vancomycin, teicoplanin

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8
Q

Inhibition of Protein Synthesis

A

Aminoglycosides: gentamicin
Macrolides: clarithromycin
Tetracyclines: doxycycline
Oxazolidinones: linezolid

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9
Q

Inhibition of Nucleic acid synthesis

A

Trimethoprim
Sulfonamides: sulfamethoxazole
Quinolones: ciprofloxacin

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