Antimicóticos sistémicos Flashcards

1
Q

Mecanismo de accion de Anfotericina B

A

Se une al esterol o ergosterol presente en la membrana de los hongo

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2
Q

Criptococos neoformans en pacientes con _________

A

Criptococos neoformans en pacientes con SIDA

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3
Q

Usos terapeuticos de Anfotericina B

A

Neutropenia y fiebre que no responde a Antibioticos de amplio espectro
En inmunosuprimidos

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4
Q

Efectos adversos de Anfotericina B (6)

A

Hipoxia
Hipotension
Acidosis tubular
Insuficiencia renal
Fiebre
Anemia hipocromica normocronica
Generales

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5
Q

Se puede dar ___________ y _________________ antes de tratamiento co Anfo B

A

Se puede dar acetaminofen e hidrocortisona antes de tratamiento co Anfo B

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6
Q

Esprectro de Flucitosina (3)

A

C neoformans
Candida
Chromomicosis

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7
Q

Usos terapeuticos de Flucitosina (1)

A

Meningitis por criptococos en sida

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8
Q

Efectos adversos de Flucitosina (4)

A

Depresion Mo
Rash
Enterocolitis
Elevacion

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9
Q

5 fluorouracilo es el antimetabolito, se puede usar en cancer

A

Verdadero

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10
Q

Imidazoles (3)

A

Clotrimazol
Miconazol
Ketoconazol
Econazol
Butoconazol
Oxiconazol
Sulconazol

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11
Q

Triazolidos (3)

A

Terconazol
Itraconazol
Fluconazol

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12
Q

Epectro de azolidos (6)

A

Candidas
Neoformans
Blastomyces dermatitidis
H capsulatum
C inmitis
Paracoccidiodes braziliensis

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13
Q

Los azolidos son dependientes al sistema enzimatico de CYP450
Verdadero o Falso

A

Verdadero

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14
Q

Los azolidos alteran la sintesis esteroidea

A

Verdadero

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15
Q

Ketoconazol se concentra en ______________ y en ___________________

A

Ketoconazol se concentra en queratinocitos y en liquido vaginal

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16
Q

Ketoconazol interactua practicamente con todo
Verdadero o Falso

A

Verdadero

17
Q

Efectos adversos de Ketoconazol (3)

A

Perdida de pelo
Rash
Piel seca

18
Q

Usos terapeuticos de Ketoconazol (7)

A

Blastomicosis
Histoplasmosis
Coccidioidomicosis
Pseudallescheriasis
Paracoccidioidomicosis
Tiña versicolor
Candidasis mucocutanea