Antilipemic Drugs Flashcards
The protein components of lipoprotein
Apolipoproteins
Drugs that reduce lipid levels
Antilipemic drugs
A fat soluble steroid found in animal fats oils egg yolk and widely distributed in the body especially in the bile blood brain tissue liver kidneys adrenal glands and Myelin sheets of nerve fibers
Cholesterol
Microscopic droplets made up of fat and protein that are produced by cells in the small intestine and released into the bloodstream
Chylomicrons
Their main purpose is to carry fats to the tissues throughout the body primarily the liver
Chylomicrons
These consist of about 90% triglycerides and small amounts of cholesterol phospholipids and proteins
Chylomicrons
Lipids originating outside the body or an organ e.g. dietary fats
Exogenous lipids
The characteristic initial lesion of atherosclerosis also known as a fatty streak
Foam cells
A class of cholesterol lowering drugs that work by inhibiting the rate limiting step in cholesterol synthesis also commonly known as or referred to as statins
Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors
A condition in which higher than normal amounts of cholesterol are present in the blood. High levels of cholesterol in other lipids may lead to the development of atherosclerosis and serious illnesses such as coronary heart disease
Hypercholesterolemia
A conjugated protein synthesized in the liver that contains varying amounts of triglycerides cholesterol phospholipids and proteins classified according to its composition and density
Lipoprotein
A class of cholesterol lowering drugs that are more formally known as HMG – CoA reductase inhibitors
Statins
Compound that consists of fatty acid and a type of alcohol known as glycerol
Triglycerides
These make up most animal and vegetable fats and are the principal lipids in the blood where they circulate bound to a protein forming high density and low density lipoprotein’s
Triglycerides
