Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

pharm 2 > Antihypertensives > Flashcards

Antihypertensives Flashcards

1
Q

When do we treat BP

A

130/80

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Primary vs secondary HT

A

primary no cause

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

difference between 1st line antihypertensives and second line what are the classes for each?

A

first -proven to decrease morbidity and mortality
1-Diuretics, ACE, ARB, CCBs
2- adrenergic antagonists-beta blockers and direct acting vasodilators

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

where are ang 1 and 11 in the body?

A

1-In the blood

11- in the lungs endothelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what does Ang 11 do? 3 be specific

A

Vasoconstricts VASCULAR smooth mm
Increases sympathetic Nervous system
Increases aldosterone-increases Na+ reabsorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What three things do ACE inhibs do?

A

Decrease peripheral resistance
decrease blood volume
decrease hypertrophy- added benefit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

ACE inhib saying

A

In ACEPRIL Brady lost a baby because of heartfail, HTN and Acute MI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What does a build up of bradkinin do in the body and one more thing about it

A

It causes inflammation angioedema, and cough

Small chance of hyperK because of decrease in aldosterone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What does aldosterone do?

A

A steroid hormone made by the adrenal cortex (the outer layer of the adrenal gland). It helps control the balance of water and salts in the kidney by keeping sodium in and releasing potassium from the body.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the difference between ARBS and ACE inhibs?

A

The site-

ARBS- block ANG 11 at site so ang 2 is still made

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Uses of ARBS 5

A

prevents HTN, scaring, renal damage, decrease in diabetic neuropothy and decrease stroke risk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

ARBs trick and 2 things

A

At the start of Arbor day. I took lithium and lost a baby

Plus hypo risks including HA and angioedema and cough are rare because there is not a build up of bradykinin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Differences in CCB

What they do and drug names

A

Dihydropyridines and non- Nifedipine
d-Vascular smooth mm

nond- Vascular smooth mm and Myocardium so works on dysR
both- HTN and Angina-Verapamil and diltrazem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

AE of nifedipine and way to remember it

A

increase dig levels=bradycardia alcohol=increase in vasodilation and drop in BP
a wet knife gives you a chub

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How to remember the dihydropyridines

A

vera likes to use a dry dildo it can decrease or increase her heart rate and she likes to drink wine because grapefruit juice increases the effects of her drug and decreases her HR shes peripheral edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Reflex tachy

A

120-130

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Beta blockers

A

Adrenergic antags beta blockers
Block fight or flight decrease bp, hr, co
LOL at a blockbuster is good for your heart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is first line for HTN

A

Diuretics, ACE, ARBS, CCBS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are the secondline tx for HTN

A

Beta blockers and Direct acting

20
Q

What are the direct acting AHTN

A

Hydralazine, Minoxidil, Nitroprusside

there is a mino reading a magazine about how to direct a pussy

21
Q

be careful with what drugs/

A

dihydro and hydrolazine
and
diltrazem-ccb and minoxidil

22
Q

Hydralazine mnemonic and 3 things

A

The magazine is mod-severly inappropriate if it goes wrong you will get a fast heart rate, stomach issues, and edema.
It only works on arterioles so no issues with ortho. For emergencies or if others fail
caution with depressed kids- MAOIS ( Decrease BP) and kidneys

23
Q

Minoxidil 2

A

The mino has hair and is more toxic than the mag

24
Q

Nitroprusside sodium

A

Only use pussy in an EMERGENCY dia- >120
it will relax your smooth mm but only for a little
You need to continually monitor it and little relfex tachy

25
Q

How is heart fail classified?

A

Heart is unable to pump sufficient blood to meet metabolic needs of the body

26
Q

R side heart fail

A

Weak- organ enlargement- esp liver

27
Q

L heart fail
2 kinds about both
and about both-3

A

Systolic - More common decrease CO from decrease in contractility
or diastolic- Too stiff to relax and cant fill CO is not afffected backs up into lungs there is pressure in the vents
Fluid retention in pulm caps hypertrophy BNP

28
Q

Causes of heart fail means and give 5 examples

A

Acceleration of weakening heart mm

Chronic HTN, Myocardial infarction, Mitral stenosis, diabetes, coronary art disease

29
Q

S/s of heart fail apear?

6 examples

A

Arise when compensation stops working
decreased CO
ventricular hypertrophy Cardiac remodeling
Activation of SNS- vasoconstriction and increased HR
increase plasma volume
decreased blood flow to the kidneys=RAAS=Na+ and H2o retention=fluidload=Cough
dif breathing when laying down.

30
Q

drugs that affect preload in heart fail 4

and one that effects SNS and one thing about it

A

Diuretics, vasodilators, ACE, ARBS

Beta blockers reverses remodeling

31
Q

What drug is the cardiac glucoside and what the uses? MA?

A

digoxin- dysR and HF increases CO and contractility

Affect sodium potassium pump- Na stays out and calcium joins=contraction

32
Q

three benefits of dig

A

increase urine output because more blood flow to the kidneys
decrease HR-more fill time
potential to reverse symptoms of CHF

33
Q

what are the AE for dig? 4 go in-depth on one

A

DysR ventricular- SCD
Dig tox
Visual disterb
HypoK- K competes for binding sites with dig if there is a decrease in k then dig tox

34
Q

Drug interactions with Dig 2

A

Beta blockers decrease HR and anything that decreases k

35
Q

Nursing considerations for dig 3

A

Long 1/2 life
hold if Hr is below 60
narrow saftey- 0.5-2.0

36
Q

What causes too much fluid in the body

A

Hypertn, heart fail, chronic kid disease, liver fail, pulmonary conditions, anascara

37
Q

What are the five types of diuretics with names and where they are located

A 
Loop-furos-loop of hen ascending
thiazides-early seg of distal convoluted tube 
k sparing spiro-distal tube
osmotic-manito- proximal tube 
carbonic anhydrase-? all?
38
Q

Teaching with diuretics 7

A 
Give in am 
weigh 2 lb 24 hour rule
K=fruits and veggies
take with food or milk 
avoid dehydration
avoid getting up fast
BP every day hold if 90/60
39
Q

loop

A

That bro henley is in the loop so he is the best he kicks out that simple guy porter and k
he is great with that kid with the disease but he is hard of hearing, he has gout and is hypoglycemic. we dont give him insulin, or dig but we do need to give him potassium

40
Q

what BP is too low

A

90/60

41
Q

thiazides

A

End in zide yay
most prescribed for HTN
That guy mic is mildly cool he is friends with henley but blocks that simple guy porter in a different spot and gets rid of k although hes a dick to that kid with the disease he can hear but he also has gout and hypoglycemia we also only dont give him insulin

42
Q

potassium sparing

A

spironolatone
This spirochete fights aldosterone but spares K but he takes 2 days to do it because he is mild. Because he spares k he may have dysR, parathesia, fatigue. We dont know if the bird is male or female but we do know they are a perv so no babies or breast feeding around them.

43
Q

What are sex characteristic names and what drug causes them

A

gynecomastia- enlargement of breast tissue
impotence-ED
menstrual abnormalities, breast tenderness and hirsutism- unwanted hair
spiro

44
Q

osmotic diuretic

A

manitol
Tx kid injury ICP Glaucoma
off label- sweetener

45
Q

Carbonic Anhydrase inhbitor

A

Acetazolamide inhibits enzyme that reabsorbs bicarb so na doesnt get reabsorbed
mild and can cause metabolic acidosis
use to tx glaucoma and motion sick

pharm 2 (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions