Antihypertensive Therapy

Question 1

Most common drug class that can lead to secondary hypertension.

Answer 1

NSAIDs.

Question 2

Therapeutic Goal for blood pressure in patients with diabetes or renal failure.

Answer 2

BP<130/80

Question 3

Therapeutic Goal for blood pressure in normal patients.

Answer 3

BP <140/90

Question 4

First line treatment for patients with hypertension and no other co-morbidities.

Answer 4

Thiazide Diuretics

Question 5

1st line treatment for patients with hypertension and previous MI. (3 classes).

Answer 5

1. Beta-blockers
2. ACE-Is
3. ARBs

Question 6

1st line treatment for patients with hypertension and exertional angina.

Answer 6

1. Beta-blockers

2. Calcium Channel Blockers

Question 7

1st line treatment hypertension with Prinzmetal Variant Angina.

Answer 7

Calcium Channel Blockers

Question 8

Treatment for hypertension with heart failure. (5 classes)

Answer 8

1. ACE-I
2. ARBs
3. Diuretics
4. Aldosterone antagonists
5. Beta-Blockers

Question 9

Treatment for hypertension with dyslipidemia (5 classes)

Answer 9

1. Alpha-blockers
2. ACE-inhibitors
3. Angiotensin receptor blockers (ARBs)
4. Calcium channel blockers
5. Indapamide

Question 10

Treatment for hypertension with diabetes (5 classes).

Answer 10

1. ACE-inhibitors
2. Angiotensin receptor blockers (ARBs)
3. Non-dihydropyridine calcium channel blockers
4. Thiazide diuretics
5. Beta-blockers

Question 11

Treatment for hypertension with chronic kidney disease (2).

Answer 11

1. ACE-inhibitors
2. Angiotensin receptor blockers (ARBs)

(Containdicated in bilateral renal artery stenosis and Caution in hyperkalemia)

Question 12

Treatment for hypertension with osteoporosis.

Answer 12

Thiazide Diuretics

Question 13

Treatment for hypertension and BPH.

Answer 13

Alpha-blockers

Question 14

Treatment for hypertension and migraine cephalgia.

Answer 14

1. Beta-blockers (non-cardioselective)

2. Non-dihydropyridine calcium channel blockers

Question 15

Class to avoid in hypertension with gout.

Answer 15

Thiazide Diuretics

Question 16

Class to avoid in hypertension with COPD or asthma.

Answer 16

Non-selective beta blockers.

in severe COPD or asthma even cardioselective beta blockers are risky

Question 17

3 classes to avoid in hypertensive patients with depression.

Answer 17

1. Central acting alpha agonists
2. Reserpine
3. Beta blockers

Question 18

2 desirable drugs in hypertension with pregnancy and two classes to avoid.

Answer 18

Use: methyldopa and hydralazine

Avoid: ACE-Is and ARBs

Question 19

2 classes to avoid in athletes with hypertension.

Answer 19

Large dose diuretics

Beta Blockers

Question 20

2 classes to avoid in sexually active men with hypertension.

Answer 20

1. Thiazide diuretics

2. beta blockers

Question 21

2 classes to avoid in truck drivers with hypertension.

Answer 21

Diuretics

central acting alpha agonists

Question 22

Best 2 classes to use for hypertension in the African American population.

Answer 22

1. Thiazide Diuretics

2. Calcium channel blockers

Question 23

Best 2 classes to use in elderly patients with isolated systolic hypertension (non-compliant vessels).

Answer 23

Diuretics

Dihydropyridine calcium channel blockers

Question 24

Class to avoid in elderly patients with orthostatic hypotension.

Answer 24

Alpha Blockers