Antihistamines And Autocoids

Question 1

Diphenhydramine

Answer 1

H1 receptor -
tx: allergies, motion sickness, prophylactic for doxorubicin
-: Anyicholinergic effects (dry mouth urine retention)
Paradoxical excitement in cats

Question 2

H1 receptor antagonists

Answer 2

Diphenhydramine
Cyrproheptadine (also serotonin receptor antagonist)
Meclizine (also anticholenergic activity)

Question 3

Famotidine

Answer 3

H2 receptor -

Dec GI acid production

Question 4

Fluoxetine

Answer 4

SSRI

Tx: OCD aggression and separation anxiety

Question 5

Cyproheptadine

Answer 5

H1 receptor - AND
nonspecific seretonin receptor -
Tx: allergic rxn and stimulate appetite(cats)

Question 6

Trazodone

Answer 6

5HT2a - AND
WEAK SSRI
Tx: anxiety and adjunct with other antidepressants

Question 7

Selegiline

Answer 7

Monoamine oxidase B - (MAO-B)

Tx: canine/feline cognitive disorder

Question 8

Meclizine

Answer 8

H1 receptor - AND
Anticholinergic activity

Antihistamine w/ antiemetic and sedative effects
Tx: vertigo

Question 9

Causes paradoxical excitement in cats

Answer 9

Diphenhydramine

Question 10

Appetite stimulant (cats mostly)

Answer 10

Cyproheptadine

Question 11

H1 antagonist with some non specific seretonin receptor antagonist action

Answer 11

Cyproheptadine

Question 12

H1 - Antiemetic used for vestibular disease

Answer 12

Meclizine

Question 13

Drug interaction of famotidine

Answer 13

Azole antifungals

Question 14

Function of Monamine oxidase B inhibitor

Answer 14

Prevents breakdown of seretonin

Question 15

Used for canine/feline cognitive disorder

Answer 15

Selegiline

Question 16

Drug interaction of selegiline

Answer 16

When used with SSRI can cause seretonin syndrome