Antihistamines Flashcards
1
Q
What are H1 antihistamines useful for?
A
- Treating dermatologic manifestations of an allergic response (like chlorpheniramine)
- Pre-operative medication for sedation, anti-emetic properties, anticholinergic effects (promethazine)
- For controlling the symptoms of parkinsonism (diphenhydramine)
2
Q
What are H2 antihistamines used for?
A
To reduce gastric acid secretion (like cimetidine - now OTC for heartburn)
3
Q
What is a common H1 antihistamine used for preop medication?
A
Promethazine
4
Q
What is the mechanism of action of H1 antihistamines?
A
Competitive Antagonism - they are competitive antihistamine receptor blockers.