Antihemophilic (IV route only) Flashcards
What disorders are treated with clotting factors?
hemophilia
liver disease
bone marrow disorders
Anti-hemophilic action
replace clotting factors that are either genetically missing or low in a particular type of hemophilia
Anti-hemophilic drug names?
Hint: end with “factor”
all meds in this category have the word “factor” in their name
Anti-hemophilic contraindications
Allergy (to the ingredients)
lactation
Anti-hemophilic cautions
pregnancy
Anti-hemophilic indications
prevent blood loss from injury or surgery
Tx bleeding disorders
Anti-hemophilic adverse effects
involve risks associated with the use of blood products
headache, flushing, fever, chills, lethargy
N & V
Stinging, itching & burning at the site of injection
Anti-hemophilic prototype
Anti-hemophilic factor
Anti-hemophilic action
normal plasma protein that is needed for the transformation of prothrombin to thrombin (the final step in the clotting pathway)
Anti-hemophilic indications
Tx of classic hemophilia to provide temporary replacement of clotting factors to correct or prevent bleeding episodes or to allow necessary surgery
Anti-hemophilic adverse effects
Allergic reaction stinging, itching, burning at injection site headache flushing rash rever chills nausea lethargy Hepatitis & Aids (from contaminated blood products)
Anti-hemophilic nursing implications
Allergy, pregnancy, lactation Baseline: Skin, heart & lung sounds CNS: perfusion (pulses) Vital Signs Labs: Clotting studies Pt is getting correct clotting factor Give by IV route only Monitor response & clotting factor levels ↓ rate of infusion if headache, chills, fever or tingling occurs Arrange to type & cross-match blood Response to drug
