Antihelminthic Drugs Flashcards
1
Q
Niclosamide is used for _________ infestation
A
Tapeworm
2
Q
What is the mechanism of action of niclosamide?
A
It blocks glucose uptake
Inhibits mitochondrial phosphorylation of ADP
3
Q
Niclosamide is lethal for _______ (parasite/ova/both)
A
Only parasite (scolex and segments)
4
Q
Niclosamide doesn’t effect the _______ (ova/worm)
A
Ova
5
Q
A _________ is given prior to oral administration of niclosamide
A
Laxative
6
Q
________ should be avoided within 1 day of niclosamide
A
Alcohol
7
Q
What are the adverse effects of miclosamide?
A
Mild GI disturbances