Antifungals Flashcards

1
Q

Clotrimazole

A

fungal ianosine demethylase inhibitor. Prevents formation of fungal cell membranes

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2
Q

Fluconazole

A

Fungal ianosine demethylase inhibitor. Used to treat vaginal candidiasis. Disrupts fungal cell membrane.

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3
Q

Nystatin

A

Ionophore. Effective against wide variety of yeasts. Disrupts cell membrane leading to formation of pores leading to leakage which causes cell death

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4
Q

Amphotericin

A

Ionophore. Disrupts cell membrane creating pores. Effective against many species of fungi

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5
Q

Griseofulvin

A

Fungal mitosis inhibitor. Activity against microsporum epidermophyton and trichophyton. thought to inhibit cell mitosis and nuclear acid synthesis

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