Antifungals Flashcards
1
Q
Clotrimazole
A
fungal ianosine demethylase inhibitor. Prevents formation of fungal cell membranes
2
Q
Fluconazole
A
Fungal ianosine demethylase inhibitor. Used to treat vaginal candidiasis. Disrupts fungal cell membrane.
3
Q
Nystatin
A
Ionophore. Effective against wide variety of yeasts. Disrupts cell membrane leading to formation of pores leading to leakage which causes cell death
4
Q
Amphotericin
A
Ionophore. Disrupts cell membrane creating pores. Effective against many species of fungi
5
Q
Griseofulvin
A
Fungal mitosis inhibitor. Activity against microsporum epidermophyton and trichophyton. thought to inhibit cell mitosis and nuclear acid synthesis