Antibiotics

Question 1

Beta-lactam antibiotic
Wide range of Gram+ and narrow range of Gram-
can be combined with what beta-lactamase inhibitor?

Answer 1

Amoxicillin

Beta-lactamase inhibitor = clavulanic acid

Question 2

Beta-lactam antibiotic

Answer 2

Methicilin

Question 3

Inhibits cell wall synthesis. Can cross blood-brain barrier

Answer 3

Cefuroxime

Question 4

Beta-lactam antibiotic used to target mainly Gram+.

Answer 4

Benzylpenicillin (Penicillin G)

Question 5

Broad-spectrum antibiotic.
30s inhibitor.
used to treat acne

Answer 5

Oxytetracycline

Question 6

Macrolide. 50s inhibitor
Used to treat multiple infections: respiratory infections, syphillis, skin infections, chronic prostatitis.
effective only against dividing organisms.
will pass into breast milk and cross placental barrier.

Answer 6

Erythromycin

Question 7

broad-spec. aminoglycoside antibiotic.
Inhibits RNA synthesis.
restricted to mycobacterial infections due to resistant strains emerging.

Answer 7

Rifampicin

Question 8

Folate antagonist - inhibits DNA synthesis.

Used to treat UTIs, bronchitis

Answer 8

Trimethoprim

Question 9

Sulfonamide drug. Competes with PABA inhibiting DNA synthesis.

Answer 9

Sulfamethoxazole

Question 10

Inhibits cell wall synthesis.

reserved as “drug of last resort” against Listeria moncytogenes, Streptococcus pyogenes, S. pneumoniae, etc.

Answer 10

Vancomycin

Question 11

Polymyxin antibiotic - phospholipid detergent.
used to treat infections due to sensitive strains of certain gram- bacilli, particularly Psuedomonas aeruginosa. Disrupts bacterial cell membrane

Answer 11

Colistin

Question 12

Quinolone - inhibits DNA synthesis.

Broad-spectrum

Answer 12

Ciprofloxacin

Question 13

Inhibits protein synthesis.

typically used in creams and eyedrops

Answer 13

Fusidic acid