Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Anti Infectives > Antifungals > Flashcards

Antifungals Flashcards

0
Q

Drugs that alter membrane function

A

Polyenes
AmphoB
Nystatin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

Fungal agents that inhibit cell wall synthesis

A

Echinocandins
End in -fungin
Parenteral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Drugs that affect ergosterol synthesis

A

-azoles and allylamines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Drugs that affect nucleic acid synthesis and replication

A

Flucytosine

Griseofulvin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Indicated for systemic/invasive infections in immunocompromised

A

Echinocandins
AmphoB
Flucytosine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Admined parenterally

A

AmphoB
Echinocandins
Some azoles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which drugs cause infusion reactions?

A

AmphoB

Echinocandins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How is the infusion reaction by AmphoB mediated?

A

Pro inflammatory cytokines
Admin ASA or APAP
Antihistamines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How is the infusion reaction by echinocandins mediated?

A

Histamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which antifungals are hepatotoxic?

A

Echinocandins

Azoles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which antifungals are nephrotoxic?

A

AmphoB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which antifungals are fungicidal?

A

Echinocandins
AmphoB
Azoles at high concentrations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which imidazole is systemically?

A

Ketoconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which triazole are systemically administered?

A

Fluconazole
Itraconazole
Voriconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which antifungal is used as prophylaxis in immunocompromised patients?

A

Posaconazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which are 2C9 inhibitor? (4)

A

Ketoconazole
Miconazole
Fluconazole
Voriconazole

16
Q

Which are 2C19 inhibitors? (4)

A

Ketoconazole
Luliconazole
Fluconazole
Voriconazole

17
Q

Which is 2E1 inhibitors?

A

Econazole

18
Q

Which are 3A4 inhibitors? (6)

A 
Ketoconazole
Luliconazole
Fluconazole
Itraconazole
Posaconazole
Voriconazole
19
Q

Which is a broad enzyme inhibitor?

A

Tioconazole

20
Q

Which suppresses bone marrow?

A

Flucytosine

Anti Infectives (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions