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Pharmacology 💊 > Antiemtics > Flashcards

Antiemtics Flashcards

1
Q

What drug class does Ondanestron (Zofran) fall under?

A

5 Ht3 or Serotonin Receptor Antagonists

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2
Q

What is the Action Of Ondanestron (zofran)?

A

PREVENTS ACTIVATION OF SERATONIN RECEPTORS

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3
Q

What do we use Ondanestron (Zofran) for?

A

N/V associated with chemo, radiation and post op patients

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4
Q

What are the adverse effects of Ondanestron (Zofran)?

A

Diarrhea, headache, dizziness, pain at injection site, Fatigue

Elevation of transient liver enzymes

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5
Q

What are the key points of Ondanestron (Zofran)?

A

serotonin syndrom and high risk for injury
pt will present with: agitation, HTN, tachycardia, and tremors

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6
Q

What is a priority effect of Ondanestronm (zofran)

A

Torsades de pointes and prolonged QT intervals

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7
Q

What drug class is Scopolamine in?

A

Anticholingeric antiemtic

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8
Q

What is the mechanism of action of scopolamine?

A

MI muscarinic receptor antagonists

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9
Q

What are the side effects of Scoplamine?

A

Anticholingeric (can’t see, pee, spit, or shit)

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10
Q

What is the therapeutic use of Scoplamine?

A

Relieves nausea and vomiting associated with MOTION SICKNESS and radiation

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11
Q

Dronabinol, how is the medication made?

A

Made from cannabinoids and marijuana derivatives

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12
Q

What is Dronabinol used for?

A

N/V caused by chemo

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13
Q

what are the adverse effects of Dronabinol

A

pyschiatric effects (euphoria, abnormal thinking, tachycardia, paranoia, drowsiness)

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14
Q

What are the risk factors with Dronabinol?

A

High abuse potential
withdrawal symptoms

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15
Q

What drug class does promethazine fall in?

A

Phenothiazine

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16
Q

What is the action of Promethazine

A

It blocks dopamine receptors in the brain

17
Q

What is promethazine used for?

A

N/V associated with surgery, anesthesia, migraines, chemo therapy and motion sickness

18
Q

What are the 2 black box warnings in Promethazine?

A

No use in <2yrs of age due to respiratory depression (don’t give to children with Reyes syndrome, sleep apnea, hepatic disease or family history of sudden infant death syndrome)

No Sub q injection, must give deep IM due to muscle and tissue damage

19
Q

what are the side effects of promethazine?

A

anticholinergic (can’t pee, can’t see, can’t spit, can’t shit)

20
Q

What drug category does Hydroxyzine fall in?

A

Antihistamine

21
Q

What is the action of hydroxyzine?

A

blocks acetycholine in brain

22
Q

What are the uses of hydroxyzine?

A

treats N/V and motion sickness, given in combo with anesthesia

23
Q

What are drug to drug interactions with hydroxyzine?

A

CNS depression with sedatives, tranquilizers, muscle relaxants, and antidepressants

24
Q

how do we administrate Hydroxyzine?

A

IM not subq

Pharmacology 💊 (8 decks)

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