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Pharmacology > Antidysrhythmic Agents > Flashcards

Antidysrhythmic Agents Flashcards

1
Q

Class IIB: Beta Blockers

A

Metoprolol (lopressor)

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2
Q

Class III Potassium Channel Blockers

A

Amiodarone

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3
Q

Class IV Calcium Channel Blockers

A
  1. Diltiazem

2. Verapamil

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4
Q

Other Antidysrhythmic Drugs

A
  1. Adenosine
  2. Digoxin
  3. Magnesium Sulfate
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5
Q 
Drugs that tx 
Atrial Flutter (ectopic focus outside of normal position)
A

Class II: Metropolol
Class IV: Verapamil

other: Anticoagulant therapy

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6
Q

Drugs that tx A- FIB (multiple focus impulses)

A

Class II : Metropolol
Class III: Amiodarone
Class IV: Diltiazem
Other: Anticoagulant Therapy

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7
Q

Drugs that tx Sustained Supraventricular Tachycardia?

A

Other: Adenosine

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8
Q

Drugs that tx Sustained Ventricular Tachycardia?

A

Class I: Lidocaine

Class III: Amiodaron

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9
Q

Drugs that tx Ventriculal Fibrillation (DEADLY)?

A

Class III: Amiodarone

Other: Epinephrine

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10
Q

Drugs that tx Digoxin-induced ventricular dysrhythmias?

A

Class I: Lidocaine

Other: IV Magnesium

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11
Q

Drugs that tx Torsade De Pointes (prolonges QT interval can lead to V-fib)?

A

Other: IV Magnesium

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12
Q

Disopyramide s/s of TOX?

A

Significant negative inotropic properties and antimuscarinic properties (dry mouth, blurred vision, constipation)

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13
Q

Lidocaine s/s of TOX?

A

Drowsiness
Slurred speech
Paresthesias
Agitation

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14
Q

Metoprolol s/s of TOX?

A 
Bradycardia
Heath Block
Fatigue
Impotence
May mask signs of hypoglycemia in diabetics
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15
Q

Amiodarone s/s of TOX?

A

Atrial Fibrillation- Pulmonary fibrosis, hepatotoxicity
Atrial Flutter- Microcystic deposits on the cornea, Thyroid dysfunction (hyper/hypo)
Ventricular tachycardia

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16
Q

Verapamil TOX?

A

CHF

17
Q

Diltiazem TOX?

A

Peripheral edema

Hypotension

18
Q

Adenosine MOA?

A
  • Supresses calcium dependent action of potentials in the SA & AV nodes
  • Decreases automaticity in the SA node and greatly slows conduction through the AV node
19
Q

Adenosine TOX?

A

Sinus bradycardia
Dyspnea
Hypotension and facial flushing
Chest discomfort

20
Q

Digoxin MOA?

A
  • Decreases conduction through the AV node
  • Decreases automaticity in the SA node
  • Can increase automaticity in the Purkinje fibers leading to dysrhythmias
21
Q

Digoxin TOX?

A

Cardiotoxicity (dysrhythmias) - risk is increased by hypokalemia, which can result form concurrent therapy with certain diuretics

GI disturbances
CNS disturbances: fatigue, visual disturbances

22
Q

Class I Sodium Channel Blockers subclasses?

A

Class IA - Disopyramide

Class IIB - LIDOCAINE

Pharmacology (8 decks)

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